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Table 1 Clinical and demographical data from subjects included in the selected studies

From: Structural brain changes associated with antipsychotic treatment in schizophrenia as revealed by voxel-based morphometric MRI: an activation likelihood estimation meta-analysis

Reference

Subjects ( n)

 

Gender of patients (F/M)

Age of patients (years)a

Education (years)a

Duration of illness

Handedness (R/L/A)

 

     Patients

     Controls

Total

     
 

Typical

Atypical

Healthy subjects*

SP

MF

      

Dazzan et al. 2005[77]

32

30

--

--

22

84

21/41

25 ± 8 to 28.4 ± 7.8

12.3 ± 1.8 to 12.3 ±2.1

19 to 22 weeksb

54/8

Girgis et al. 2006[78]

--

15

15

15

--

30

8/7

23.6 ± 5.9

13.1 ± 3.2

105.3 ± 94.6 weeksa

NA

Whitford et al. 2006[79]

--

25

26

25

--

51

10/15

22.1 ± 3.2

NA

5.9 ± 8.2 monthsa

21/4

Douaud et al. 2007[80]

--

25

25

--

--

50

7/18

15.9 ± 1.5 to 16.5 ± 1.3

NA

1.4 ± 0.7 yeara

20/5

Théberge et al. 2007[81]

16

16

16

--

32

2/14

25 ± 8

11-13

243 ± 120 weeksa

12/3/1

Stip et al. 2009[82]

--

15

--

15

--

15

4/11

28.3 ± 9.07

10.6 ± 3.5

5.8 ± 6.2 yearsa

NA

Tomelleri et al. 2009[83]

25

45

79

--

--

149

25/45

39.73 ± 10.94

NA

14.13 ± 10.7 yearsa

67/3

Deng et al. 2009[84]

6

14

11

--

--

31

11/9

26 ± 10 to 29.9 ± 13.5

NA

NA

18/2

Chua et al. 2009[85]

15

5

--

--

25

45

10/10

29 ± 8.6

12 ± 2.9

40.8 ± 50.8 weeksa

NA

Molina et al. 2011[86]

--

30

31

--

--

61

14/16

34.1 ± 10.6

NA

13.4 ± 5.9 yearsa

NA

  1. *Matched for age and gender to the patients groups; a= mean ± SD; b = median (±SD); NA= data not available; SP = same patients evaluated repeatedly in longitudinal comparisons; MF = medication-free subjects.