Table 1 Rates of reduction used in previous research
From: Study protocol: safety correction of high dose antipsychotic polypharmacy in Japan
Tanabe’s research [9] | |||||
Group | Mean dose before reduction | Reduction speed | GAF | SOI | n |
Successful | 1,372 mg CP | 40.4 mg CP/week | 34.1 | 4.5 | 37 |
Unsuccessful | 1,832 mg CP | 95.4 mg CP/week | 29.8 | 4.8 | 11 |
Murasugi’s research [10] | |||||
Group | Mean dose before reduction | Reduction speed | GAF | SOI | n |
Successful | 1,581 mg CP | 43.0 mg CP/week | 35.2 | 4.8 | 5 |
Unsuccessful | 2,389 mg CP | 97.4 mg CP/week | 44.0 | 4.5 | 5 |
Combination of both studies | |||||
Group | Mean dose before reduction | Reduction speed | GAF | SOI | n |
Successful | 1,397 mg CP | 40.7 mg/week | 33.5 | 4.5 | 42 |
Unsuccessful | 2, 006 mgCP | 96.0 mg/week | 34.2 | 4.7 | 16 |