Study protocol: safety correction of high dose antipsychotic polypharmacy in Japan

BMC Psychiatry

Table 3 Reduction protocol for low-potency drugs

Generic name	Product name	Maximum reduction rate^†(mg/week)	Maximum reduction^‡(mg)
Sulpiride	Dogmatyl, others	50	100
Sultopride	Barnetil	50	100
Pipamperone	Propitan	50	100
Chlorpromazine	Contomin, others	25	50
Levomepromazine	Levotomin, others	25	50
Carpiprammine	Defecton	25	50
Oxypertine	Forit	20	40
Zotepine	Lodopin, others	16.5	33
Quetiapine	Seroquel	16.5	33
Clocapramine	Clofekton	10	20
Mosapramine	Cremin	8.25	16.5
Propericiazine	Neuleptil	5	10
Prochlorperazine	Novamin	3.75	7.5
Moperone	Luvatren	3.125	6.25

^†Maximum reduction rate represents the maximum acceptable reduction per week.
^‡Maximum reduction represents the maximum amount of reduction at a time. After maximum reduction, subsequent reduction is performed after a minimum 2-week observation period.
(Cited and partially modified from Sukegawa [11]).

ISSN: 1471-244X