Table 1 Clinical and demographic characteristics of melancholic (Mel), non-melancholic (N-Mel) and control groups

Age

41.7 (13.5)

42.4 (9.1)

38.6 (15.2)

§ t = -0.19, p = 0.85 ‡ t = 0.68, p = 0.85 † t = 0.96, p = 0.34

% Female

65%

65%

55%

§ χ ² = 0.00, p = 1.00 ‡ χ ² = 0.42, p = 0.52 † χ ² = 0.42, p = 0.52

Years of education

14.4 (2.7)

14.1 (2.7)

17.1 (3.7)

§ t = 0.43, p = 0.41 ‡ t = -2.66, p <0.01 † t = -3.00, p <0.01

Estimated IQ

108.1 (8.5)

109.2 (6.4)

114.3 (11.8)

§ t = -0.46, p = 0.65 ‡ t = -1.91, p = 0.06 † t = -1.70, p = 0.10

QIDS-SR ¹⁶

16.6 (4.0)

16.6 (4.4)

0.9 (1.2)

§ t = 0.00, p = 1.00 ‡ t = 16.92, p <0.01 † t = 15.39, p <0.01

STAI-State

49.1 (15.3)

48.3 (9.7)

28.7 (8.1)

§ t = 0.19, p = 0.85 ‡ t = 5.28, p <0.01 † t = 7.00, p <0.01

STAI-Trait

59.1 (11.4)

62.9 (8.3)

34.2 (7.4)

§ t = -1.20, p = 0.24 ‡ t = 8.17, p <0.01 † t = 11.55, p <0.01

CORE (Non-interactiveness)

4.4 (3.3)

0.9 (1.7)

-

§ t = 4.28, p <0.01

CORE (Retardation)

4.9 (4.1)

1.6 (2.9)

-

§ t = 3.00, p <0.01

CORE (Agitation)

1.5 (2.4)

0.2 (0.7)

-

§ t = 2.38, p < 0.05

CORE Total

10.8 (7.6)

2.7 (4.4)

-

§ t = 4.14, p <0.01

GAF

54.3 (15.6)

67.5 (9.7)

94.5 (2.2)

§ t = -3.23, p <0.01 ‡ t = -11.43, p <0.01 † t = -12.17, p <0.01

SSRI% yes (n)

30% (6)

40% (8)

-

§ χ ² = 9.69, p <0.01

Other med% yes (n)

80% (16)

35% (7)

-

§ χ ² = 27.22, p <0.01