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Table 2 Summary of pooled effects at post-treatment

From: A systematic review and meta-analysis of randomised controlled trials of peer support for people with severe mental illness

Outcome

Trials

Participants

Effect size (95% CI)

Heterogeneity: I 2 ;Chi2 (p value)

Follow-up (months)

GRADE confidence rating

Mutual Support

4

2369

    

Hospitalisation [51]

1

80

RR = 0.50 (0.23, 1.11)

N/A

10

Very low1,4,5

Symptoms of psychosis

0

N/A

N/A

N/A

N/A

N/A

Employment

0

N/A

N/A

N/A

N/A

N/A

Quality of life [47]

1

300

SMD = -1.42 (-1.69, – 1.16)

N/A

12

Very low1,4,5

Overall psychiatric symptoms [49]

1

162

N/A “no difference in change”

N/A

N/A

N/A

Depression and anxiety [47]

1

300

SMD = -0.42 (-0.66, – 0.18)

N/A

12

Very low1,4,5

Recovery [47]

1

300

SMD = -0.11 (-0.35, 0.13)

N/A

12

Very low1,4,5

Hope [49]

1

162

N/A “no difference in change”

N/A

N/A

N/A

Empowerment [42, 47, 49]

3

2266

SMD = -1.44 (-2.79, – 0.09)

99%; 186.26 (p < 0.001)

8-12

Very low1,2,4,5

Satisfaction

0

N/A

N/A

N/A

N/A

N/A

Peer-support

11

2805

    

Hospitalisation [38]

1

45

RR = 1.07 (0.55, 2.07)

N/A

9-12

Very low1,4,5

Duration of admission [38, 44, 48]

3

255

SMD = -0.22 (-0.72, 0.28)

72%; 7.16 (p = 0.03)

 

Very low1,2,4,5

Symptoms of psychosis [36, 45]

2

696

SMD = -0.08 (-0.27, 0.03)

N/A

2-12

Low4,5

Employment

0

N/A

N/A

N/A

N/A

N/A

Quality of life [36, 39, 45, 48, 50]

5

1039

SMD = 0.04 (-0.16, 0.24)

52%; 8.38 (p = 0.08)

3-12

Very low1,4,5

Depression and anxiety [36, 41, 45]

3

861

SMD = -0.10 (-0.24, 0.03)

0%; 1.97 (p = 0.37)

2-12

Low4,5

Overall psychiatric symptoms [41, 45, 48]

3

753

SMD = -0.07 (-0.39, 0.24)

74%; 7.83 (p = 0.02)

3-9

Very low 1,2,4,5

Recovery [36, 39, 45, 46]

4

1066

SMD = -0.24 (-0.39, – 0.09)

27%; 4.09 (p = 0.25)

2-12

Low4,5

Hope (SMD) [39, 45, 46, 50]

4

1072

SMD = -0.14 (-0.27, -0.02)

7%; 3.21 (p = 0.36)

2-3

Very low 1,4,5

Empowerment [39, 50]

2

286

SMD = -2.67 (-7.35, 2.02)

97%; 38.87 (p < 0.001)

3

Very low1,2*,4,5

Satisfaction [38, 41, 48]

3

332

SMD = 0.02 (-0.20, 0.23)

0%; 0.95 (p = 0.62)

9-12

Very low1,4,5

Peer delivered services

3

411

    

Hospitalisation [40]

1Ψ

114

RR = 0.68 [0.45, 1.03]

N/A

24

Very Low1,4,5

Symptoms of psychosis

0

N/A

N/A

N/A

N/A

N/A

Employment [28]

1

96

N/A “no differences”

N/A

N/A

N/A

Quality of life (SMD) [28]

1

96

N/A “no differences”

N/A

N/A

N/A

Depression and anxiety

0

N/A

N/A

N/A

N/A

N/A

Overall psychiatric symptoms

0

N/A

N/A

N/A

N/A

N/A

Recovery

0

N/A

N/A

N/A

N/A

N/A

Hope

0

N/A

N/A

N/A

N/A

N/A

Empowerment

0

N/A

N/A

N/A

N/A

N/A

Satisfaction [28]

1

87

SMD = 0.48 (0.05, 0.91)

N/A

12

Very low1,4,5

  1. This table shows the number of trials and participants assigned for each comparison. For each outcome, it lists the number of trials and participants included in the analysis.
  2. Reasons for downgrade: 1Risk of bias, 2Inconsistency, 3Indirectness, 4Imprecision, 5Publication/Reporting Bias.
  3. RR Relative Risk, SMD Standardised Mean Difference.
  4. Ψ Solomon [28] measured the outcome and reported no difference.