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Table 10 Medications with Health Canada–approved indications for anxiety and related disorders

From: Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

  Anxiety disorders Panic disorder Social anxiety disorder Obsessive–compulsive disorder Generalized anxiety disorder Posttraumatic stress disorder
ANTIDEPRESSANTS       
SSRIs       
Escitalopram (Cipralex®)     X X  
Fluoxetine (Prozac®)     X   
Fluvoxamine (Luvox®)     X   
Paroxetine (Paxil®)   X X X X X
Paroxetine CR (Paxil® CR)   X X    
Sertraline (Zoloft®)   X   X   
TCAs       
Clomipramine     X   
Other antidepressants       
Venlafaxine XR (Effexor® XR)   X X   X  
Duloxetine (Cymbalta®)      X  
AZAPIRONES       
Buspirone (BuSpar®, Buspirex®)      X  
BENZODIAZEPINES* X      
  1. Data from respective Canadian product monographs [84].
  2. *Multiple generic and brand name products, consult product monographs: alprazolam, bromazepam, chlordiazepoxide, clorazepate, diazepam, lorazepam, and oxazepam are indicated for anxiety disorders; alprazolam is also indicated for panic disorder.
  3. CR = controlled release; SSRI = selective serotonin reuptake inhibitor; TCA = tricyclic antidepressant; XR = extended release.
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