Skip to main content

Table 7 Benzodiazepines versus typical antipsychotics – 7 trials, 206 participants

From: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

Main outcomes

Benz.

Control

RR (95% CI)

Not improved by 90 minutes

20/72

32/75

0.64 (0.4–0.98)

Needing another injection

24/31

31/35

0.66 (0.42–1.02)

Mental state: asleep – by 3 hours

31/74

21/74

1.6 (0.99–2.5)

Leaving the study early

14/101

16/105

0.87 (0.5–1.5)

Adverse effects: needing antiparkinsonian medication

4/31

9/35

0.50 (0.2–1.5)