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Table 4 Sensitivity analyses: adjustment for confounding factors

From: Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons

 

EFFECT

RESPONSE

DROPOUTS

 

mean

Confidence interval

Est. bet. st. variance*

mean

Confidence interval

Est. bet. st. variance*

value

Confidence interval

Est. bet. st. variance*

AGE

            

   venlafaxine

0.25

0.11

0.40

0.002

0.90

0.49

1.31

0.049

0.26

-0.09

0.61

0.000

   Fluoxetine

0.13

-0.14

0.39

0.097

-0.10

-0.37

0.17

0.000

0.23

-0.14

0.60

0.000

MALE PERCENT

            

   venlafaxine

0.16

-0.01

0.33

0.008

0.66

0.21

1.12

0.096

0.23

-0.13

0.59

0.001

   Fluoxetine

0.12

-0.14

0.38

0.010

-0.17

-0.43

0.08

0.000

0.31

-0.02

0.64

0.000

DURATION

            

   venlafaxine

0.23

0.07

0.39

0.009

0.56

0.18

0.95

0.047

0.13

-0.23

0.48

0.000

   Fluoxetine

0.10

-0.16

0.36

0.100

-0.21

-0.45

0.03

0.000

0.34

0.02

0.67

0.000

DOSAGE

            

   venlafaxine

0.22

0.06

0.37

0.008

0.70

0.26

1.15

0.096

0.22

-0.12

0.56

0.000

   Fluoxetine

0.19

-0.10

0.48

0.094

-0.05

-0.38

0.27

0.000

0.19

-0.19

0.57

0.000

IMPUTATION

            

   venlafaxine

0.22

0.06

0.37

0.008

0.74

0.29

1.18

0.093

0.18

-0.18

0.54

0.000

   Fluoxetine

0.11

-0.14

0.36

0.096

-0.20

-0.44

0.04

0.000

0.27

-0.06

0.60

0.000

  1. * estimated between study variance