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Table 1 SIGH-SAD Outcome Measures at Randomization and after 1, 2, 3 and 4 weeks of treatment.

From: A controlled trial of the Litebook light-emitting diode (LED) light therapy device for treatment of Seasonal Affective Disorder (SAD)

  Mean SIGH SAD score* Mean SIGH SAD score As % of randomization score % Participants in remission (SIGH SAD <9)
  Active Control Active Control p value Active Control p value
Randomization 28.0 ± 5.3 25.1 ± 3.2 - - - - - -
Week 1 18.6 ± 7.9 19.0 ± 7.2 67.1 ± 26.7 74.0 ± 22.5 0.527 7.1 11.1 0.999
Week 2 14.9 ± 10.0 17.9 ± 4.9 54.5 ± 36.4 71.7 ± 19.5 0.208 28.6 0.0 0.127
Week 3 11.1 ± 10.1 14.9 ± 4.2 39.0 ± 30.7 54.4 ± 17.9 0.080 42.9 11.1 0.176
Week 4 8.7 ± 8.4 13.4 ± 5.4 29.9 ± 25.4 54.4 ± 21.8 0.027** 57.1 11.1 0.040***
  1. Notes: Observed cases analysis: for active treatment n = 14 and for placebo treatment n = 9. * interaction of time and treatment significant in repeated measures ANOVA as noted in text. ** comparison significant at p ≤ 0.05 by t test. *** comparison significant at p ≤ 0.05 by Fisher's exact test.