From: Duloxetine in the treatment of major depressive disorder: an open-label study
 | Baseline, mean (SD) | Endpoint, mean (SD) | p-valuea |
---|---|---|---|
Hamilton Rating Scale for Depression total score (n = 511) | 23.7 (3.6) | 9.9 (7.7) | T = -39.1, df = 510, p < .001 |
Hamilton Rating Scale for Depression subscales (n = 511) | Â | Â | Â |
   Core | 9.5 (1.7) | 3.4 (3.7) | T = -37.2, df = 510, p < .001 |
   Maier | 12.2 (2.0) | 4.5 (4.4) | T = -38.1, df = 510, p < .001 |
   Anxiety/Somatization | 7.6 (1.9) | 3.6 (2.7) | T = -30.7, df = 510, p < .001 |
   Retardation | 8.2 (1.5) | 3.4 (3.1) | T = -35.3, df = 510, p < .001 |
   Sleep | 3.8 (1.7) | 1.7 (1.8) | T = -23.5, df = 510, p < .001 |
Clinical Global Impression of Severity (n = 512) | 4.6 (0.6) | 2.3 (1.3) | T = -36.1, df = 511, p < .001 |
Patient Global Impression of Improvement (n = 511) | N/A | 2.6 (1.4) | N/A |