Table 2 Baseline characteristics of patients associated with each cluster.
Cluster 1 n = 64 | Cluster 2 n = 92 | Cluster 3 n = 36 | Cluster 4 n = 30 | |
|---|---|---|---|---|
Age, y mean (SD) | 42.8 (11.8) | 40.8 (11.9) | 39.7 (12.0) | 40.9 (13.3) |
Male, % | 46.9 | 38.0 | 47.2 | 36.7 |
White Ethnicity, % | 79.7 | 82.6 | 75.0 | 86.7 |
Weight, kg mean (SD) | 77.8 (19.4) | 81.4 (20.7) | 82.7 (22.5) | 75.6 (20.9) |
YMRS total, mean (SD) | 29.9 (6.1) | 25.5 (4.6) | 25.6 (4.7) | 31.2 (6.7) |
YMRS-09: Disruptive-aggressive behavior, mean (SD) | 2.0 (1.6) | 2.2 (1.5) | 1.7 (1.3) | 2.1 (1.5) |
YMRS-10: Appearance, mean (SD)† | 1.3 (1.1) | 0.6 (0.9) | 0.5 (0.8) | 1.3 (1.0) |
HAMD-21 total, mean (SD) | 13.6 (7.7) | 14.6 (7.6) | 16.8 (5.5) | 11.5 (6.2) |
Mixed episode, % | 28.1 | 58.7 | 58.3 | 13.3 |
Psychotic features, % | 65.6 | 26.1 | 30.6 | 73.3 |
Rapid cycling, % | 39.1 | 66.3 | 63.9 | 56.7 |
# manic episodes previous year, mean (SD) | 2.9 (5.4) | 3.9 (5.6) | 8.2 (10.7) | 2.9 (4.9) |
Randomized to olanzapine, % | 46.9 | 60.9 | 33.3 | 43.3 |