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Table 5 Significant Predictors of Weight Gain

From: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis

Variable

HR

95% CI

Interpretation

Change from baseline in FACTOR 1 (Cognitive Restraint)

0.81b

0.73–0.90

Patients experiencing a decrease in cognitive restraint were more likely to gain weight and patients experiencing an increase in cognitive restraint were less likely to gain weight.

Change from baseline in EBA-1 (Hunger)

1.32a

1.07–1.64

Patients experiencing an increase in hunger were more likely to gain weight and patients experiencing a decrease in hunger were less likely to gain weight.

Change from baseline in EBA-8 (Overeating)

1.28a

1.07–1.53

Patients experiencing an increase in overeating were more likely to gain weight and patients experiencing a decrease in overeating were less likely to gain weight.

  1. Abbreviations: CI = confidence interval; EBA = Eating Behaviors Assessment; HR = hazard ratio.
  2. Pooled analysis across all 3 studies
  3. HR was adjusted for study effect and other variables included in the model (baseline BMI was also included, although it was not significant, p = .543)
  4. ap < .01;bp < .0001