Skip to main content

Table 2 Number of positive individuals (%) according to the Edinburgh Postnatal Depression Scale (EPDS), sensitivity, specificity, PPV, NPV, accuracy ( 95% confidence intervals) for different EPDS cutoff points compared to the gold standard (International Neuropsychiatric Interview) and Youden's index, adult population from Pelotas (n = 447), 2012

From: Validation of the Edinburgh postnatal depression scale (EPDS) for screening of major depressive episode among adults from the general population

Cutoff points N (%) Sensitivity (CI 95%) % Specificity (CI 95%) % PPV % NPV % Accuracy % Youden’s index (*)
≥ 1 363 (81.2) 100.0 (91.2 – 100.0) 20.6 (16.8 – 24.9) 11.0 (8.0 – 14.7) 100.0 (95.7 – 100.0) 60.3 (58.4 – 62.3) 0.206
≥ 2 303 (67.8) 97.5 (86.8 – 99.9) 35.1 (30.5 – 40.0) 12.9 (9.3 – 17.2) 99.3 (96.2 – 100.0) 66.3 (62.9 – 70.0) 0.326
≥ 3 239 (53.5) 95.0 (83.1 – 99.4) 50.6 (45.6 – 55.6) 15.9 (11.5 – 21.2) 99.0 (96.6 – 99.9) 72.8 (68.6 – 77.0) 0.456
≥ 4 196 (43.8) 90.0 (76.3 – 97.2) 60.7 (55.8 – 65.5) 18.4 (13.2 – 24.5) 98.4 (96.0 – 99.6) 75.3 (70.1 – 80.6) 0.507
≥ 5 150 (33.6) 82.5 (67.2 – 92.7) 71.3 (66.6 – 75.6) 22.0 (15.7 – 29.5) 97.6 (95.2 – 99.0) 76.9 (70.5 – 83.2) 0.538
≥ 6 122 (27.3) 82.5 (67.2 – 92.7) 78.1 (73.8 – 82.1) 27.0 (19.4 – 35.8) 97.8 (95.6 – 99.1) 80.3 (74.0 – 86.6) 0.606
≥ 7 102 (22.8) 82.5 (67.2 – 92.7) 83.0 (79.0 – 86.6) 32.4 (23.4 – 42.3) 98.0 (95.9 – 99.2) 82.8 (76.5 – 89.0) 0.655
≥ 8 85 (19.0) 80.0 (64.4 – 90.9) 87.0 (83.3 – 90.1) 37.6 (27.4 – 48.8) 97.8 (95.7 – 99.0) 83.5 (77.0 – 90.0) 0.670
≥ 9 67 (15.0) 72.5 (56.1 – 85.4) 90.7 (87.4 – 93.3) 43.3 (31.2 – 56.0) 97.1 (94.9 – 98.5) 81.6 (74.4 – 88.7) 0.632
≥10 61 (13.6) 70.0 (53.5 – 83.4) 91.9 (88.8 – 94.4) 45.9 (33.1 – 59.2) 96.9 (94.6 – 98.4) 80.9 (73.6 – 88.3) 0.619
≥ 11 53 (11.9) 65.0 (48.3 – 79.4) 93.4 (90.5 – 95.6) 49.1 (35.1 – 63.2) 96.4 (94.1 – 98.0) 79.2 (71.6 – 86.8) 0.584
≥ 12 43 (9.6) 55.0 (38.5 – 70.7) 94.8 (92.2 – 96.8) 51.2 (35.5 – 66.7) 99.5 (93.0 – 97.3) 74.9 (67.0 – 82.8) 0.498
≥ 13 33 (7.4) 47.5 (31.5 – 63.9) 96.6 (94.3 – 98.1) 57.6 (39.2 – 74.5) 94.9 (92.4 – 96.8) 72.0 (64.1 – 79.9) 0.441
≥ 14 29 (6.5) 45.0 (29.3 – 61.5) 97.3 (95.2 – 98.6) 62.1 (42.3 – 79.3) 94.7 (92.1 – 96.7) 71.1 (63.3 – 79.0) 0.423
≥ 15 23 (5.1) 35.0 (20.6 – 51.7) 97.8 (95.8 – 99.0) 60.9 (38.5 – 80.3) 93.9 (91.1 – 96.0) 66.4 (58.9 – 73.9) 0.328
≥ 16 18 (4.0) 25.0 (12.7 – 41.2) 98.0 (96.2 – 99.1) 55.6 (30.8 – 78.5) 93.0 (90.2 – 95.2) 61.5 (54.7 – 68.3) 0.230
≥ 17 15 (3.4) 22.5 (10.8 – 38.5) 98.5 (96.8 – 99.5) 60.0 (32.3 – 83.7) 92.8 (90.0 – 95.1) 60.5 (53.9 – 67.1) 0.210
≥ 18 12 (2.7) 20.0 (9.1 – 35.6) 99.0 (97.5 – 99.7) 66.7 (34.9 – 90.1) 92.6 (89.8 – 94.9) 59.5 (53.2 – 65.8) 0.190
≥ 19 10 (2.2) 17.5 (7.3 – 32.8) 99.3 (97.9 – 99.8) 70.0 (34.8 – 93.3) 92.4 (89.6 – 94.7) 58.4 (52.4 – 64.4) 0.168
≥ 20 10 (2.2) 17.5 (7.3 – 32.8) 99.3 (97.9 – 99.8) 70.0 (34.8 – 93.3) 92.4 (89.6 – 94.7) 58.4 (52.4 – 64.4) 0.168
≥ 21 7 (1.6) 12.5 (4.2 – 26.8) 99.5 (98.2 – 99.9) 71.4 (29.0 – 96.3) 92.0 (89.1 – 94.4) 56.0 (50.8 – 61.2) 0.120
≥ 22 6 (1.3) 12.5 (4.2 – 26.8) 99.8 (98.6 – 100) 83.3 (35.9 – 99.6) 92.1 (89.1 – 94.4) 56.1 (50.9 – 61.3) 0.123
≥ 23 4 (0.9) 10.0 (2.8 – 23.7) 100.0 (99.1 – 100.0) 100.0 (39.8 – 100.0) 91.9 (88.9 - 94.2) 55.0 (50.3 - 59.7) 0.100
  1. Note: PPV = positive predictive value; NPV = negative predictive value.
  2. (*) Youden’s índex = [sensitivity + specificity - 1].