Table 1 Details of the 10 primary studies included in this meta-analysis
Year | Author | Disorder | Patients | Controls | Depression | PET Software And | Medication | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Sample Size | Gender | Mean Age (SD) | Sample Size | Gender | Mean Age (SD) | Severity HDRS) | FWHM | Â |
2001 | Saxena [23] | MDD | 27 | 13 M, 14 F | 38.2(11.1) | 17 | 8 M, 9 F | 32.5(11.7) | 17 20.8(5.0) | SPM 96, 16 mm | * |
2001 | Brody [24] | MDD | 24 | 11 M, 13 F | 38.9(11.4) | 16 | 8 M, 8 F | 35.6(18.3) | 17, 19.4(5.5) | SPM 96, 10 mm | ** |
2001 | Kennedy [25] | MDD | 13 | 13 M | 36(10) | 24 | 24 M | 31.7(6.7) | 17 22.4(3.6) | SPM 96, 8 mm | treated with antidepressants |
2002 | Kimbrell [7] | MDD | 37 | 13 M, 24 F | 43.4(13.0) | 37 | 13 M, 24 F | 43.4(12.5) | 28, 16.9(8.3) | SPM 95, 10 mm | medication-free |
2003 | Kegeles [26] | MDD | 19 | 6 M, 13 F | 16(11) | 10 | 4 M, 6 F | 39(19) | 17, 22.3(3.9) | SPM 96, 8 mm | medication-free at least 14 days |
2005 | Zhang [27] | MDD | 14 | 4 M, 10 F | 43.8(9.3) | 11 | 3 M, 8 F | 43.0(7.8) | 17, 27.8(6.2) | SPM 2b, 8 mm | treated with antidepressants |
2006 | Su [4] | MDD | 6 | 2 M, 4 F | 71(6) | 10 | 4 M, 6 F | 67.6(2.9) | 24, 39.7(3.2) | SPM 2, 10 mm | first episode and medication-free |
2007 | Aihara [28] | MDD | 24 | 9 M, 15 F | 52.4(13.4) | 23 | 8 M, 15 F | 54.8(12.6) | 21, 32.0 ± 6.8 | SPM 99, 10 mm | medication-free |
2009 | Smith [29] | MDD | 16 | 6 M, 10 F | 65.3(9.1) | 13 | 5 M, 8 F | 67.4(7.4) | 24, 26.0(3.5) | SPM 99, 8 mm | medication-free |
2009 | Wu [30] | MDD | 8 | 5 M, 3 F | 47.1(9.3) | 8 | 5 M, 3 F | 45.1(8.2) | 17, 23.1(3.9) | SPM 2b, 8 mm | medication-free |