Skip to main content

Table 1 Details of the 10 primary studies included in this meta-analysis

From: Cerebral metabolism in major depressive disorder: a voxel-based meta-analysis of positron emission tomography studies

Year Author Disorder Patients Controls Depression PET Software And Medication
    Sample Size Gender Mean Age (SD) Sample Size Gender Mean Age (SD) Severity HDRS) FWHM  
2001 Saxena [23] MDD 27 13 M, 14 F 38.2(11.1) 17 8 M, 9 F 32.5(11.7) 17 20.8(5.0) SPM 96, 16 mm *
2001 Brody [24] MDD 24 11 M, 13 F 38.9(11.4) 16 8 M, 8 F 35.6(18.3) 17, 19.4(5.5) SPM 96, 10 mm **
2001 Kennedy [25] MDD 13 13 M 36(10) 24 24 M 31.7(6.7) 17 22.4(3.6) SPM 96, 8 mm treated with antidepressants
2002 Kimbrell [7] MDD 37 13 M, 24 F 43.4(13.0) 37 13 M, 24 F 43.4(12.5) 28, 16.9(8.3) SPM 95, 10 mm medication-free
2003 Kegeles [26] MDD 19 6 M, 13 F 16(11) 10 4 M, 6 F 39(19) 17, 22.3(3.9) SPM 96, 8 mm medication-free at least 14 days
2005 Zhang [27] MDD 14 4 M, 10 F 43.8(9.3) 11 3 M, 8 F 43.0(7.8) 17, 27.8(6.2) SPM 2b, 8 mm treated with antidepressants
2006 Su [4] MDD 6 2 M, 4 F 71(6) 10 4 M, 6 F 67.6(2.9) 24, 39.7(3.2) SPM 2, 10 mm first episode and medication-free
2007 Aihara [28] MDD 24 9 M, 15 F 52.4(13.4) 23 8 M, 15 F 54.8(12.6) 21, 32.0 ± 6.8 SPM 99, 10 mm medication-free
2009 Smith [29] MDD 16 6 M, 10 F 65.3(9.1) 13 5 M, 8 F 67.4(7.4) 24, 26.0(3.5) SPM 99, 8 mm medication-free
2009 Wu [30] MDD 8 5 M, 3 F 47.1(9.3) 8 5 M, 3 F 45.1(8.2) 17, 23.1(3.9) SPM 2b, 8 mm medication-free
  1. Note: FWHM = Full Width at Half Maximum, SPM = Statistical Parametric Mapping, M = man, F = female, HDRS = Hamilton Depression Rating Scale.
  2. *Either treatment naïve or off medication for more than 1 year.
  3. **Either treatment naïve or off medication at least 2 weeks.