Table 3 Frequency of prescribed drugs in the bipolar sample

Mood Stabilizers

  Lithium

165 (49.1)

74 (43.8)

30 (65.2)

61 (50.4)

6.77

.034

  Carbamazepine

10 (3.0)

2 (1.2)

4 (8.7)

4 (3.3)

7.14

.028

  Lamotrigine

32 (9.5)

22 (13.0)

3 (6.5)

7 (5.8)

4.84

.089

  Valproate

100 (29.8)

38 (22.5)

19 (41.3)

43 (35.5)

9.14

.010

  Topiramate

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

-

-

FGA

52 (15.5)

16 (9.5)

15 (32.6)

21 (17.4)

15.31

<.000*

SGA

226 (67.3)

109 (64.5)

33 (71.7)

84 (69.4)

1.26

.532

  Quetiapine

138 (41.1)

70 (41.4)

21 (45.7)

47 (38.8)

.66

.721

  Aripiprazole

38 (11.3)

22 (13.0)

2 (4.3)

14 (11.6)

2.72

.256

  Clozapine

18 (5.4)

5 (3.0)

4 (8.7)

9 (7.4)

3.96

.138

  Risperidone

40 (11.9)

13 (7.7)

7 (15.2)

20 (16.5)

5.81

.055

  Olanzapine

21 (6.3)

14 (8.3)

2 (4.3)

5 (4.1)

2.40

.301

  Ziprasidone

1 (0.3)

1 (0.6)

0 (0.0)

0 (0.0)

0.99

.609

Pregabalin

17 (5.1)

8 (4.7)

1 (2.2)

8 (6.6)

1.44

.486

Antidepressants

198 (58.9)

121 (71.6)

14 (30.4)

63 (52.1)

28.99

<.000*

  TCAs

91 (27.1)

56 (33.1)

5 (10.9)

30 (24.8)

9.58

.008

  IMAOs

3 (0.9)

3 (1.8)

0 (0.0)

0 (0.0)

2.99

.224

  SSRIs

32 (9.5)

17 (10.1)

2 (4.3)

13 (10.7)

1.70

.428

  SNRIs

75 (22.3)

49 (29.0)

3 (6.5)

23 (19.0)

11.73

.003

  Other

11 (3.3)

6 (3.6)

1 (2.2)

4 (3.3)

0.217

.897

Polypharmacy (total)

170 (50.6)

94 (55.6)

23 (50)

53 (43.8)

3.94

.139

Lithium + other MS

46 (13.7%)

17 (10.1%)

16 (34.8%)

13 (10.8%)

19.98

<.000*

Lithium + SGAs

119 (35.5%)

48 (28.4%)

28 (60.9%)

43 (35.8%)

16.64

<.000*