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Table 3 Adjusted ORs from multivariable logistic regression for association between statin prescription and subsequent diagnosis of depression between 2006-2008, by increasing age group ( n= 4,607,990)

From: Statin use and risk of depression: a Swedish national cohort study

  Age ≥40 yrs Age ≥50 yrs Age ≥60 yrs Age ≥70 yrs
  OR a 95% CI p-value OR a 95% CI p-value OR a 95% CI p-value OR a 95% CI p-value
Statin prescriptions             
Any statin 0.95 0.91-0.99 0.016 0.91 0.87-0.95 <0.001 0.85 0.81-0.89 <0.001 0.81 0.76-0.87 <0.001
Simvastatin 0.93 0.89-0.97 0.001 0.90 0.86-0.94 <0.001 0.85 0.81-0.90 <0.001 0.82 0.76-0.87 <0.001
Pravastatin 0.90 0.74-1.09 0.268 0.84 0.69-1.04 0.104 0.80 0.64-1.01 0.061 0.72 0.54-0.96 0.026
Fluvastatin 0.98 0.65-1.46 0.914 0.91 0.59-1.39 0.660 0.89 0.55-1.43 0.662 1.03 0.60-1.78 0.906
Atorvastatin 1.11 1.01-1.22 0.032 1.04 0.94-1.16 0.427 0.95 0.84-1.07 0.384 0.93 0.80-1.10 0.412
Rosuvastatin 1.21 0.92-1.60 0.177 1.18 0.88-1.60 0.274 1.10 0.75-1.60 0.635 1.21 0.71-2.04 0.485
  1. CI = confidence interval; OR = odds ratio.
  2. aThe model includes prescription of statin medication (any statin, and by individual statins) and the following variables as covariates: gender, age (40-49, 50-59, 60-69, 70+), marital status, education (three levels), family income (quartiles), hospitalisation for cardio-pulmonary disease, hospitalisation for alcoholism, hospitalisation for coronary heart disease, and region (large cities, Southern, Northern).