Table 1 Patient demographics and clinical characteristics at baseline
|  | Overall (n  = 60) | Insufficient response (n  = 39) | Insufficient tolerability (n  = 21) |
|---|---|---|---|
Gender, n (%) | |||
 Male | 37 (61.7) | 22 (56.4) | 15 (71.4) |
 Female | 23 (38.3) | 17 (43.6) | 6 (28.6) |
Age, years (SD)c | 38.0 (10.7) | 40.5 (10.5)* | 33.3 (9.9)* |
Marital status, n (%)a | |||
 Single | 42 (70.0) | 25 (64.1) | 17 (81.0) |
 Married | 11 (18.3) | 9 (23.1) | 2 (9.5) |
 Divorced | 4 (6.7) | 3 (7.7) | 1 (4.8) |
 Widowed | 2 (3.3) | 2 (5.1) | 0 (0.0) |
Employment status, n (%)a | |||
 Employed | 12 (20.0) | 8 (20.5) | 4 (19.0) |
 Student/Retired | 4 (6.7) | 1 (2.6) | 3 (14.3) |
 Unemployed | 43 (71.7) | 30 (76.9) | 13 (61.9) |
Psychiatric history | |||
 Disease duration, years (SD) | 12.5 (9.3) | 13.2 (9.6) | 11.3 (8.8) |
 Number of schizophrenic episodes over lifetime, n (SD) | 3.6 (2.7) | 3.2 (2.1) | 4.3 (3.5) |
 Presence of family members with schizophrenia, n (%) | 9 (15.0) | 4 (10.3) | 5 (23.8) |
Psychoactive medication at base, n (%) | |||
 Any antipsychotics | 59b (98.3) | 38b (97.4) | 21 (100.0) |
  Risperidone | 15 (25.0) | 8 (20.5) | 7 (33.3) |
  Quetiapine IR | 11 (18.3) | 8 (20.5) | 3 (14.3) |
  Sulpiride | 9 (15.0) | 8 (20.5) | 1 (4.8) |
  Amisulpride | 6 (10.0) | 3 (7.7) | 3 (14.3) |
  Aripiprazole | 5 (8.3) | 3 (7.7) | 2 (9.5) |
  Olanzapine | 5 (8.3) | 3 (7.7) | 2 (9.5) |
  Ziprasidone | 4 (6.7) | 3 (7.7) | 1 (4.8) |
  Clozapine | 3 (5.0) | 1 (2.6) | 2 (9.5) |
Mean (SD) baseline scores | |||
 PANSS | 84.4 (17.7) | 85.9 (17.5) | 81.7 (18.2) |
 CGI-S | 4.7 (0.7) | 4.7 (0.7) | 4.7 (0.7) |