Validation of the PAUSS. (A) Intercorrelations of the PAUSS and ADOS with age and WAIS estimated total IQ (Spearman rank) (B) Intercorrelations of individual PAUSS items (Spearman rank) and the Autism Diagnostic Observation Schedule (ADOS). (C) Significant differences were obtained for the PAUSS by ADOS-diagnosis group (ADOS ≥ 12: autism; ADOS ≥ 7: autism spectrum; ADOS < 7: no autism). (D, E) No significant differences were found for AQ and EQ by ADOS-diagnosis group. (F) Receiver Operating Characteristic curves for PAUSS and ADOS illustrate high Area under the Curve (AuC) statistics and thus high predictive power of both instruments. (G) Receiver Operating Characteristic curves for AQ and EQ illustrate low Area under the Curve (AuC) statistics and thus low predictive power of both instruments. P-values were obtained from analysis of covariance with age and IQ as covariates.