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Table 2 Significant differences in cortical thickness and surface area between patients with bipolar disorder, patients with major depressive disorder and healthy controls after controlling for age, IQ and total intracranial volume

From: Distinguishing bipolar and major depressive disorders by brain structural morphometry: a pilot study

 

Measure

 

Annotation

log(p)

Size (mm^2)

Talairach coordinates

Number of vertices

X

Y

Z

BD > MDD

area.pial

L

bankssts

3.576

224.15

-58.5

-43.8

10.0

458

precentral

3.138

584.71

-51.4

3.2

18.7

1280

inferiorparietal

2.812

313.97

-42.2

-72.9

25.6

534

superiorparietal

2.670

107.18

-20.3

-68.9

35.3

208

precuneus

2.171

124.20

-10.4

-55.1

44.7

251

R

middletemporal

3.419

812.33

62.4

-46.4

-0.5

1762

HC > BD

area.pial

L

posteriorcingulate

2.658

175.49

-2.7

-24.4

26.5

486

thickness

R

caudalanteriorcingulate

2.182

105.74

3.4

9.5

25.8

259

HC < BD

area.pial

L

postcentral

-2.931

195.56

-44.9

-30.0

49.8

494

precuneus

-2.528

196.41

-20.2

-65.8

24.6

375

supramarginal

-2.340

160.41

-50.3

-48.5

37.0

374

R

superiortemporal

-3.884

702.71

44.3

-28.1

-4.7

1641

insula

-2.684

153.36

39.8

-24.0

-1.9

464

supramarginal

-2.204

127.56

52.7

-24.5

23.1

307

HC > MDD

thickness

L

medialorbitofrontal

3.008

837.10

-12.5

43.8

0.7

1429

parsopercularis

2.894

670.07

-37.6

8.3

12.6

1926

middletemporal

2.504

292.69

-42.4

6.8

-35.0

340

area.pial

L

rostralmiddlefrontal

2.922

427.44

-39.4

20.9

30.0

832

HC < MDD

area.pial

L

insula

-2.870

170.71

-34.0

-0.2

14.7

482

R

supramarginal

-2.393

91.08

51.0

-24.6

21.8

215

  1. p < 0.01, uncorrected, number of vertices > 200. L left hemisphere, R right hemisphere. HC Healthy Controls (n = 29), MDD Major Depressive Disorder (n = 19), BD Bipolar Disorder (n = 16)