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Table 2 Significant differences in cortical thickness and surface area between patients with bipolar disorder, patients with major depressive disorder and healthy controls after controlling for age, IQ and total intracranial volume

From: Distinguishing bipolar and major depressive disorders by brain structural morphometry: a pilot study

  Measure   Annotation log(p) Size (mm^2) Talairach coordinates Number of vertices
X Y Z
BD > MDD area.pial L bankssts 3.576 224.15 -58.5 -43.8 10.0 458
precentral 3.138 584.71 -51.4 3.2 18.7 1280
inferiorparietal 2.812 313.97 -42.2 -72.9 25.6 534
superiorparietal 2.670 107.18 -20.3 -68.9 35.3 208
precuneus 2.171 124.20 -10.4 -55.1 44.7 251
R middletemporal 3.419 812.33 62.4 -46.4 -0.5 1762
HC > BD area.pial L posteriorcingulate 2.658 175.49 -2.7 -24.4 26.5 486
thickness R caudalanteriorcingulate 2.182 105.74 3.4 9.5 25.8 259
HC < BD area.pial L postcentral -2.931 195.56 -44.9 -30.0 49.8 494
precuneus -2.528 196.41 -20.2 -65.8 24.6 375
supramarginal -2.340 160.41 -50.3 -48.5 37.0 374
R superiortemporal -3.884 702.71 44.3 -28.1 -4.7 1641
insula -2.684 153.36 39.8 -24.0 -1.9 464
supramarginal -2.204 127.56 52.7 -24.5 23.1 307
HC > MDD thickness L medialorbitofrontal 3.008 837.10 -12.5 43.8 0.7 1429
parsopercularis 2.894 670.07 -37.6 8.3 12.6 1926
middletemporal 2.504 292.69 -42.4 6.8 -35.0 340
area.pial L rostralmiddlefrontal 2.922 427.44 -39.4 20.9 30.0 832
HC < MDD area.pial L insula -2.870 170.71 -34.0 -0.2 14.7 482
R supramarginal -2.393 91.08 51.0 -24.6 21.8 215
  1. p < 0.01, uncorrected, number of vertices > 200. L left hemisphere, R right hemisphere. HC Healthy Controls (n = 29), MDD Major Depressive Disorder (n = 19), BD Bipolar Disorder (n = 16)