Table 1 Characteristics of the study cohort (N = 238,963) at baseline
Characteristic | n | % | |
|---|---|---|---|
Gender | |||
Male | 92,935 | 38.89 | |
Female | 146,028 | 61.11 | |
Age (years) | |||
20-29 | 51,212 | 21.43 | |
30-39 | 77,141 | 32.28 | |
40-49 | 59,260 | 24.80 | |
50-59 | 39,573 | 16.56 | |
60-64 | 11,777 | 4.93 | |
Mean age (SD) | |||
Overall | 39.54 (11.14) | ||
Male | 40.98 (11.13) | ||
Female | 38.61 (11.04) | ||
Ethnicity | |||
White/not recorded | 227,451 | 95.18 | |
Indian | 1922 | 0.80 | |
Pakistani | 1714 | 0.72 | |
Bangladeshi | 1000 | 0.42 | |
Other Asian | 991 | 0.41 | |
Caribbean | 1520 | 0.64 | |
Black African | 1386 | 0.58 | |
Chinese | 307 | 0.13 | |
Other/mixed | 2672 | 1.12 | |
Depression severity (index diagnosis) | |||
Mild | 171,208 | 71.65 | |
Moderate | 59,140 | 24.75 | |
Severe | 8615 | 3.61 | |
Perinatal depressiona | 18,259 | 12.50 | |
Smokingb | |||
Recorded | 233,290 | 97.63 | |
Non smoker | 110,849 | 47.52 | |
Ex smoker | 35,132 | 15.06 | |
Current smoker | 87,309 | 37.43 | |
Light smoker (1–9 per day) | 24,104 | 10.33 | |
Moderate smoker (10–19 per day) | 40,546 | 17.38 | |
Heavy smoker (≥20 per day) | 22,659 | 9.71 | |
Alcohol consumptionb | |||
Recorded | 203,189 | 85.03 | |
Non drinker | 55,253 | 27.19 | |
Trivial (less than 1 unit per day) | 77,579 | 38.18 | |
Light (1–2 units per day) | 51,310 | 25.25 | |
Moderate (3 to 6 units per day) | 14,482 | 7.13 | |
Heavy (7 to 9 units per day) | 2174 | 1.07 | |
Very heavy (over 9 units per day) | 2391 | 1.18 | |
Townsend deprivation quintileb | |||
Recorded | 230,762 | 96.57 | |
1 (Least deprived) | 45,021 | 19.51 | |
2 | 46,207 | 20.02 | |
3 | 48,293 | 20.93 | |
4 | 47,063 | 20.39 | |
5 (Most deprived) | 44,178 | 19.14 | |
Comorbidities | |||
CHD | 4109 | 1.72 | |
Diabetes | 7371 | 3.08 | |
Hypertension | 17,217 | 7.20 | |
Stroke/TIA | 1741 | 0.73 | |
Cancer | 3810 | 1.59 | |
Epilepsy/seizures | 3325 | 1.39 | |
Hypothyroidism | 5267 | 2.20 | |
Obsessive-compulsive disorder | 494 | 0.21 | |
Rheumatoid arthritis | 1301 | 0.54 | |
Osteoarthritis | 7228 | 3.02 | |
Osteoporosis | 867 | 0.36 | |
Liver disease | 698 | 0.29 | |
Renal disease | 549 | 0.23 | |
Asthma/chronic obstructive airways disease | 31,816 | 13.31 | |
Medications at baseline | |||
Anticonvulsants | 2672 | 1.12 | |
Antihypertensives | 25,344 | 10.61 | |
Anti-psychotics | 836 | 0.36 | |
Aspirin | 7159 | 3.00 | |
Anticoagulants | 1073 | 0.45 | |
Bisphosphonates | 854 | 0.36 | |
Hypnotics/anxiolytics | 11,354 | 4.75 | |
NSAIDs | 12,725 | 5.33 | |
Statins | 10,823 | 4.53 | |
Oral contraceptivesa | 27,396 | 18.76 | |
HRTa | 7207 | 4.94 | |