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Table 3 Cost-effectiveness results – base-case analysis

From: Is adjunctive pharmacotherapy in attention-deficit/hyperactivity disorder cost-effective in Canada: a cost-effectiveness assessment of guanfacine extended-release as an adjunctive therapy to a long-acting stimulant for the treatment of ADHD

 

Long-acting stimulant monotherapy

GXR + long-acting stimulant

Incrementala

Average QALYs

0.627

0.655

0.028

Patient-weeks with response

12.46

19.03

6.57

Drug costs, $CA

337

1,072

735

Medical costs, $CA

612

545

−67

Productivity losses, $CA

2,633

2,299

−334

Total cost, $CA

MoH perspective

949

1,617

668

Total cost, $CA

Societal perspective

3,582

3,915

334

Incremental cost/QALY, $CA

MoH perspective

  

$CA23,720/ QALY

Incremental cost/QALY, $CA

Societal perspective

  

$CA11,845/QALY

Incremental cost/patient-week with response, $CA

MoH perspective

  

$CA102/responder

Incremental cost/patient-week with response, $CA

Societal perspective

  

$CA51/responder

  1. aMay not sum to total because of rounding
  2. GXR guanfacine extended release, MoH Ministry of Health, QALY quality-adjusted life year