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Table 1 Participant characteristics and global tissue volumes in women recovered from anorexia nervosa versus healthy controls

From: Normal gray matter volumes in women recovered from anorexia nervosa: a voxel-based morphometry study

  RAN
(n = 22)
HC
(n = 22)
Two-sample t-test
Characteristic Mean ± SD Mean ± SD t (df) P d
Age 27.32 ± 5.14 26.14 ± 4.64 0.80 (42) .43 0.24
BMI (kg/m2)a 20.39 ± 1.66 21.85 ± 1.76 −2.70 (38) .01 −0.85
BDI 6.36 ± 7.94 1.77 ± 2.69 2.57 (42) .02 0.77
EDE-Q global score 0.84 ± 0.74 0.19 ± 0.17 4.04 (42) <.001 1.21
STAI state score 32.14 ± 8.16 25.86 ± 5.21 3.04 (42) .004 0.92
STAI state score 38.77 ± 11.48 28.36 ± 6.43 3.71 (42) .001 1.12
GM volume (ml) 635.96 ± 52.03 664.39 ± 44.81 1.94 (42) .06 −0.59
WM volume (ml) 474.31 ± 51.71 479.70 ± 39.19 0.39 (42) .70 −0.12
CSF volume (ml) 224.82 ± 30.61 232.19 ± 21.40 0.93 (42) .36 −0.28
TIV (ml) 1335.09 ± 115.62 1376.28 ± 87.11 1.34 (42) .19 −0.40
GM fraction (GM divided by TIV) 0.477 ± 0.021 0.483 ± 0.015 1.06 (42) .30 −0.33
WM fraction (WM divided by TIV) 0.355 ± 0.017 0.348 ± 0.014 −1.39 (42) .17 0.45
CSF fraction (CSF divided by TIV) 0.168 ± 0.015 0.169 ± 0.012 0.17 (42) .87 −0.07
Lowest lifetime weightb 71.84 ± 9.18 (range: 46–85)  
Lowest lifetime BMI (kg/m2)c 14.76 ± 1.83 (range: 10–17)  
Age of AN onset 17.36 ± 4.17 (range: 11–32)  
Duration of illness (months)d 32.86 ± 27.47 (range: 6–120)  
Duration of recovery (months)d 51.62 ± 42.70 (range: 12–192)  
  1. BDI Beck depression inventory, BMI Body mass index, CSF Cerebrospinal fluid, d Cohen’s d effect size, EDE-Q Eating disorder examination-questionnaire, GM Gray matter, HC Healthy controls, ml milliliters, RAN Recovered anorexia nervosa, STAI State-trait anxiety inventory, TIV Total intracranial volume, WM White matter
  2. aData not available for three recovered anorexia nervosa women and one healthy control
  3. bExpressed as percentage of ideal weight, taking into account height, age and gender
  4. cNot adjusted for age
  5. dData not available for one recovered anorexia nervosa woman