Skip to main content

Advertisement

Table 2 Risks of psychiatric disorders, suicide attempt and suicide in siblings of individuals with EDS (EDS siblings), compared with matched siblings to individuals without EDS (comparison siblings)

From: Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings

  EDS siblings (n = 1,722) Comparison siblings (n = 16,920)   
  n (%) n (%) RR (95 % CI) RRa (95 % CI)
Autism spectrum disorder 10 (0.6) 56 (0.4) 1.8 (0.9–3.4) 1.7 (0.9–3.2)
Bipolar disorder 7 (0.5) 69 (0.4) 1.0 (0.5–2.0) 0.9 (0.4–2–0)
ADHD 26 (1.5) 123 (0.7) 2.1 (1.4–3.3) 2.1 (1.4–3.3)
Depression 72 (4.2) 492 (2.9) 1.5 (1.1–1.8) 1.4 (1.1–1.8)
Suicide attempt 66 (3.8) 364 (2.1) 1.8 (1.4–2.3) 1.8 (1.4–2.3)
Suicide 10 (0.6) 44 (0.3) 2.1 (1.2–3.9) 2.3 (1.3–4.1)
Schizophrenia 7 (0.4) 54 (0.3) 1.3 (0.6–2.7) 1.4 (0.6–3.1)
  1. Associations are expressed as risk ratios (RR) and 95 % confidence intervals (95 % CIs) from conditional logistic regression
  2. Note: statistically significant RR are bolded. RRa, risk ratios restricted to individuals born in Sweden