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Table 3 IPTW adjusted association between depression treatment and healthcare expenditures stratified by coexisting condition type. Among medicaid beneficiaries with type 2 diabetes mellitus and newly diagnosed depression. Multi-state medicaid claims database – 2000–2008

From: Depression treatment decreases healthcare expenditures among working age patients with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed depression

  ALL expenditures T2DM-related expenditures
Depression treatment categories Change 95 % CI Sig Change 95 % CI Sig
Dominant
 Only antidepressants −0.23 −0.41 0.01   −0.23 −0.44 0.06  
 Only psychotherapy −0.48 −0.59 −0.34 *** −0.41 −0.55 −0.23 ***
 Antidepressants and Psychotherapy −0.41 −0.57 −0.19 ** −0.24 −0.48 0.1  
Concordant ONLY
 Only antidepressants −0.21 −0.33 −0.08 ** −0.05 −0.22 0.16  
 Only psychotherapy −0.11 −0.26 0.06   −0.19 −0.36 0.03  
 Antidepressants and Psychotherapy −0.23 −0.38 −0.04 * −0.27 −0.44 −0.06 *
Discordant only
 Only antidepressants −0.18 −0.31 −0.02 * −0.09 −0.26 0.13  
 Only psychotherapy −0.09 −0.29 0.18   −0.1 −0.33 0.2  
 Antidepressants and Psychotherapy −0.29 −0.45 −0.08 * −0.1 −0.35 0.23  
Both concordant & discordant
 Only antidepressants −0.1 −0.2 0.01   −0.1 −0.23 0.06  
 Only psychotherapy −0.21 −0.31 −0.09 *** −0.34 −0.45 −0.19 ***
 Antidepressants and Psychotherapy −0.27 −0.38 −0.15 *** −0.1 −0.28 0.14  
  1. Reference Group: No Depression Treatment
  2. Note: Study sample was comprised of adults with type 2 diabetes mellitus aged 18–64 years with at least one coexisting dominant, concordant, or discordant chronic physical condition and who were alive, not dually eligible for Medicare, and continuously enrolled in fee-for-service Medicaid for at least 24 months (N = 5295); includes Medicaid data from three states: Illinois, Texas, New York
  3. All healthcare expenditures included inpatient, outpatient and prescription drug-related expenditures; T2DM-related expenditures included inpatient and outpatient expenditures due to T2DM-related diagnosis. The expenditures were log transformed
  4. Asterisks indicate statistical significance and are based on mixed effects models; ***P < .001; **.001 ≤ P < .01; *.01 ≤ P < .05
  5. T2DM Type 2 Diabetes Mellitus; depression: Major Depressive Disorder; IPTW Inverse Probability Treatment Weights, SE Standard Error