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Table 2 Regions of significantly different GMD in MDD patients compared to healthy controls

From: What is the impact of child abuse on gray matter abnormalities in individuals with major depressive disorder: a case control study

Anatomical Region Side BA MNI coordinate, mm Number of voxel Zscore
    x y z   
Increased gray matter density in MDD
 Postcentral gyrus L 4 −39 −27 52 210 3.99
 Postcentral gyrus R 4 36 −24 54 518 5.05
 Parieto-occipital cortex L 31 −8 −70 26 140 3.45
 Parieto-occipital cortex R 23 4 −64 18 166 3.91
 Putamen L   −26 4 −4 1219 4.90
 Putamen R   26 8 −6 2174 5.05
 Thalamus R   4 −27 2 3687 4.80
 Hippocampus L   −16 −36 −4   4.44
 Hippocampus R   24 −33 −1   4.98
 Cerebellum (Declive) L   −20 −75 −20 175 3.46
 Cerebellum (Tuber of vermis) R   3 −76 −26 621 4.19
Decreased gray matter density in MDD
 Orbitofrontal cortex L   −14 46 −18 139 4.08
 Orbitofrontal cortex R 11 20 62 −20 224 3.93
 Dorsomedial prefrontal cortex R 8 15 32 54 149 3.72
 Dorsal anterior cingulate cortex R 24 6 −21 39 153 3.45
 Middle occipital gyrus L   −36 −87 22 292 4.16
 Middle occipital gyrus R 18 38 −88 −8 497 4.71
 Cuneus L 17 −8 −98 10 245 4.40
  1. Note: L left hemisphere, R right hemisphere, BA Brodmann’s area; the threshold was set at AlphaSim corrected p < 0.05