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Table 2 Multivariate regression analyses for clinical outcome and pro-inflammatory cytokines

From: Metabolic syndrome and adverse clinical outcomes in patients with bipolar disorder

  Previous hospitalizations (times) Dyskinesia (AIMS) Insight(SAI) Global function (GAF) Executive function(WCST)
Standardized coefficient (ß)
(95% C.I.)
P value Standardized coefficient (ß)
(95% C.I.)
P value Standardized coefficient (ß)
(95% C.I.)
P value Standardized coefficient (ß) (95% C.I.) P value Standardized coefficient (ß)
(95% C.I.)
P value
Age −0.18 0.848 0.190 0.020** −0.063 0.479 −0.054 0.526 −0.392 P < 0.001**
(−0.062,0.051) (0.03,0.094) (−0.092,0.043) (−0.208,0.107) (−0.628,-0.205)
Gender
 Male -- -- -- --    -- -- -- --
 Female 0.205 0.021** 0.203 0.020** 0.190 0.026** −0.144 0.079 −0.044 0.653
(0.238,2.918) (0.215,2.419) (0.224,3.464) (−7.21,0.397) (−5.945,3.741)
Smoking 0.072 0.415 0.141 0.105 0.049 0.565 −0.238 0.004** −0.137 0.154
(−0.870,2.095) (−0.209,2.169) (−1.240,2.262) (−10.170,-1.962) (−0.9007,1.445)
Bipolar disorder subtype
 Type I -- -- -- --    -- -- -- --
 Type II −0.197 0.028** −0.408 0.684 0.294 0.001** −0.009 0.911 −0.041 0.670
(−2.775,-0.162) (−1.305,-0.858) (1.194,4.385) (−3.944,3.522) (−5.739,3.704)
Pharmacological treatment duration (years) 0.259 0.005** 1.165 0.246 0.258 0.004** 0.154 0.071 0.083 0.401
(0.028,0.153) (−0.021,0.080) (0.035,0.183) (−0.014,0.332) (−0.127,0.315)
Psychiatric medication group
 Mood stabilizers only -- -- -- --    -- -- -- --
 Atypical antipsychotics only 0.185 0.071 0.094 0.355 0.054 0.586 −0.321 0.001** −0.219 0.039**
(−0.163,3.848) (−0.852,2.357) (−1.707,3.006) (−15.003,-3.928) (−15.303,-0.396)
 Atypical antipsychotics plus mood stabilizers 0.089 0.383 0.049 0.630 0.139 0.164 −0.312 0.001** −0.218 0.042**
(−0.829,2.143) (−0.937,1.543) (−0.534,3.124) (−11.365,-2.805) (−10.721,-0.196)
Metabolic syndrome (+) 0.19 0.036** 2.190 0.030** −0.179 0.036** −0.164 0.046** −0.324 0.042**
(0.097,2.918) (0.121,2.387) (−3.447,-0.118) (−7.891,-0.071) (−9.969,-0.178)
  1. ** p<0.05
  2. The bold-italic data emphasized the statistical significance