Association between non-compliance with psychiatric treatment and non-psychiatric service utilization and costs in patients with schizophrenia and related disorders

Table 2 Psychiatric and non-psychiatric costs by adherence and persistence patterns

	Non-adherent (N = 2774)		Adherent (N = 2774)		B	p	Non-persistent (N = 1956)		Persistent (N = 1956)		B	p
	Mean	SD	Mean	SD	B	p	Mean	SD	Mean	SD	B	p
Psychiatric-related costs
Total costs	3061	5101	3907	5954	−783.3	<0.001	1553	3170	3317	5341	−974.8	<0.001
Copayments	343	826	420	973	−74.8	0.001	251	617	445	938	−69.4	<0.001
Government payments	2697	4585	3463	5307	−705.0	<0.001	1293	2759	2845	4632	−897.7	<0.001
Non-psychiatric related
Total costs	1900	6527	211	1450	1401.3	<0.001	3039	8532	327	1673	1614.1	<0.001
Copayments	243	988	28	259	163.9	<0.001	397	1238	52	291	200.1	<0.001
Government payments	1628	5715	181	1220	1219.7	<0.001	2605	7538	266	1373	1403.0	<0.001
Total psychiatric and non-psychiatric-related costs
Total costs	4961	7867	4118	6109	617.996	0.0010	4592	8803	3644	5626	639.302	0.0100
Copayments	586	1261	448	1009	89.090	0.0020	648	1355	497	1003	717.831	0.0010
Government payments	4324	7004	3644	5434	514.649	0.0020	3899	7801	3112	4863	505.311	0.0190

**p < 0.001; adherence is defined as the percentage of days of psychiatric prescription (PDP) ≥ 80% and non-adherence as a PDP < 80%; currency unit = 1,000 Korean Won; data were collected from patients with schizophrenia and related disorders; the covariates included sex, age, duration of follow up, and insurance type (national health insurance or another type)

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