Childhood neglect predicts the course of major depression in a tertiary care sample: a follow-up study

BMC Psychiatry

Table 3 Predictors of course of MDD – Cox proportional hazard models, multivariate analysis

Predictors of time to remission/recovery from index MDE^a (n = 119)	HR^b	95% CI	P value
Marital status – single, separated, divorced or widowed	0.53	0.32–0.88	0.01
Length of index MDE – chronic	0.45	0.26–0.76	0.003
Comorbid anxiety disorder	0.60	0.36–0.98	0.04
Childhood Physical neglect	0.43	0.22–0.86	0.02
Predictors of time to recurrences^a (N = 65)
Age at onset of MDD	0.97	0.911–1.03	0.29
Length of index MDE – chronic	0.48	0.17–1.33	0.16
Number of previous MDEs ≥ 3	3.91	1.26–12.1	0.02
Childhood Emotional neglect	3.69	1.13–11.9	0.03
Childhood Physical neglect	1.15	0.38–3.41	0.81

Legend: MDE major depressive episode, MDD major depressive disorder ^aReference categories: Marital status: married or common-law; Length of index MDE: <2 years; Comorbid anxiety disorder: absent; Length of index MDE: <2 years; Number of previous MDEs: <3; Childhood neglect: absent ^bAdjusted for sex, age and length of follow-up

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