Table 5 Association between individual risk factors for QT-related arrhythmias and Torsades de Pointes (TdP), and TdP risk category of antipsychotics
AP Torsades de Point risk category, n (%) | |||||
|---|---|---|---|---|---|
Factor | A | B | C | χ 2 | P-value |
Presence of comorbid somatic illnesses | 82 (50.6) | 556 (48.6) | 29 (69.0) | 6.9 | 0.03 |
Presence of cardiac comorbidities | 2 (1.2) | 45 (3.9) | 4 (9.5) | 6.8a | 0.03 |
Presence of vascular comorbidities | 10 (6.2) | 123 (10.8) | 11 (26.2) | 14.0 | 0.01 |
Use of pharmacological treatments determining QT prolongation during AP therapy | 134 (82.7) | 885 (77.4) | 41 (97.6) | 11.6 | 0.003 |