BMC Psychiatry

Table 2 Treatment by time effect of DCS on PANSS and SANS

From: Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study

		Week within treatment phase								Analysis
	Treatment	Baseline		Week 2		Week 4		Week 6		treatment x time
		Mean	SD	Mean	SD	Mean	SD	Mean	SD	F	p
PANSS
Positive	DCS	14.39	5.71	14.42	5.87	14.03	5.86	14.06	5.89	0.51	0.61
	PCB	14.72	5.79	14.19	5.46	14.11	5.16	13.97	5.62
Negative	DCS	20.47	7.12	20.19	6.97	20.19	6.64	19.86	7.04	0.37	0.69
	PCB	20.58	6.87	20.31	7.01	20.00	6.57	19.56	7.11
General	DCS	34.44	8.14	33.69	8.36	33.81	8.75	33.56	8.58	1.70	0.18
	PCB	35.22	8.11	34.56	7.78	33.97	7.26	33.83	8.48
SANS
I	DCS	13.97	8.39	13.56	8.65	13.67	8.51	13.36	8.40	0.34	0.79
	PCB	14.03	8.25	13.86	7.88	13.17	7.81	13.44	7.95
II	DCS	7.92	4.92	7.39	5.06	7.31	4.83	7.11	4.89	0.44	0.72
	PCB	8.22	4.67	7.75	4.78	7.19	4.71	7.22	4.75
III	DCS	10.14	4.26	9.89	4.45	9.78	4.32	9.61	4.32	0.50	0.62
	PCB	10.00	3.92	9.67	4.24	9.61	4.32	9.78	4.18
IV	DCS	12.44	5.34	12.22	5.53	12.08	5.26	12.08	5.44	0.18	0.84
	PCB	12.50	5.01	12.33	5.35	12.14	5.16	12.47	5.36
V	DCS	5.97	3.61	5.61	3.63	5.44	3.39	4.94	3.43	0.66	0.58
	PCB	5.78	3.69	5.64	3.77	4.78	3.39	5.03	3.34
Summary	DCS	11.75	4.72	11.33	4.76	11.14	4.59	10.78	4.74	0.79	0.44
	PCB	11.42	4.76	11.39	4.56	10.83	4.58	10.89	4.59
Total	DCS	50.44	21.88	48.67	22.57	48.28	21.69	47.11	22.55	0.52	0.62
	PCB	50.53	20.81	49.25	20.70	46.89	20.42	47.94	20.95

PANSS, Positive and Negative Syndrome Scale; SANS, Scale for the Assessment of Negative Symptoms; SD, standard deviation; ‘Baseline’ indicates Week 0 for the first phase and Week 9 (after 3 week washout period) for the second phase

Back to article page

ISSN: 1471-244X

Contact us

Submission enquiries: bmcpsychiatry@biomedcentral.com
General enquiries: ORSupport@springernature.com