Brain donation in psychiatry: results of a Dutch prospective donor program among psychiatric cohort participants

BMC Psychiatry

Table 2 the approach of cohort participants, by disorder

Disorder	Cohort	Approached (n)	Average age (y)	Male	Accepted info1	Permission to phone	Info2	Registered
SCZ	GROUP	39	37	82%	n/a^b	100%	23%	3%
BD	BiG, DIADE	947	53	46%	99%	95%	59%	25%
MDD	NESDA, NESDO, ECT	1139	54	31%	90%	84%	37%	9%
OCD	AMC regular & DBS, NOCDA	493	48	46%	95%	82%	21%	5%^c
PTSD	BEPP/EMDR, BioMap, Booster, Paroxetine/CGT, PO	265^a	48	52%	n/a	57%	16%	6%
Family	GROUP, BiG, NESDA	403	61	45%	100%	94%	39%	17%
Control	GROUP, BiG, NESDA, NESDO, Booster, DIADE	465	53	39%	92%	88%	32%	8%
Total		3751	53	41%	95%	86%	39%	13%

NESDA = The Netherlands Study of Depression and Anxiety. NESDO = The Netherlands study of Depression in the Elderly. ECT = Depressed patients treated with electroconvulsive therapy. BiG = Bipolar Genetics. DIADE = Diagnostic Imaging of Affective Disorders using Emotion Processing. GROUP = Genetic Risk and Outcome in Psychosis. AMC regular = Patients who had a diagnostic intake or were treated for OCD at the Academic Medical Center in Amsterdam. AMC DBS = Patients with OCD who underwent deep brain stimulation at the AMC. NOCDA = The Netherlands OCD Association Study: identifying risk factors for chronicity in the course of obsessive-compulsive disorder. Booster = The effect of oxytocin on brain activity in police officers. Paroxetine/CGT = Randomized controlled trial ‘the effectiveness of paroxetine versus trauma-focused cognitive behavioral therapy in the treatment of PTSD’. BioMap = The ‘biological markers for PTSD’ study. BEP/EMDR = ‘Effectiveness and efficiency of Eye Movement Desensitization and Reprocessing therapy (EMDR) versus Brief Eclectic Psychotherapy (BEP) in the treatment of PTSD’. PO = Police officers who have been treated for PTSD at the Academic Medical Center
^a30% (n = 40) of BEPP/EMDR participants could not be reached by phone, possibly due to outdated contact information
^bn/a = non applicable, because info1 was sent by post
^cThose treated with Deep Brain Stimulation (n = 10) registered significantly more often (30%)

ISSN: 1471-244X