Efficacy and cost-effectiveness of a blended cognitive behavioral therapy for depression in Spanish primary health care: study protocol for a randomised non-inferiority trial

Table 3 The study measures and assessment times

Variable	Instrument	Screening baseline		3 months		6 months		12 months
		Online	Phone	Online	Phone	Online	Phone	Online	Phone
Questions for patients
Demographics and history of mental health treatments			x
Diagnostic interview	M.I.N.I.		x						x
Symptoms of depression	PHQ-9 QUIDS SR-16	x		x		x		x
Quality of life	EQ-5D-5 L AQol	x		x		x		x
Health care uptake and productivity at work	TiC-P		x		x		x		x
Treatment preference			x
Patient expectancy of treatment	CEQ	x
Working alliance	WAI-SF			x
Technology alliance	TAI-OT^a			x
Client satisfaction	CSQ			x
Satisfaction with the online program	SUS^a			x
Questions for therapists
Working alliance	WAI-SF			x
Satisfaction with the online program	SUS^a			x

M.I.N.I MINI International Neuropsychiatric Interview, PHQ-9 Patient Health Questionnaire-9, QUIDS SR-16 Quick Inventory of Depressive Symptomatology-16, EQ-5D-5 L EuroQol 5D, AQol Assessment of Quality of Life, TiC-P Trimbos and iMTA Questionnaires on Costs Associated with Psychiatric Illness, CEQ Credibility and Expectancy Questionnaire, WAI-SF, Working Alliance Inventory, TAI-OT WAI Online Therapy, CSQ Client Satisfaction Questionnaire, SUS System Usability Scale
^aThis instrument will be administered in the b-CBT condition

ISSN: 1471-244X