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Table 3 Logistic regression showing odd ratios associated with TRD-UP instead of BP disorder (N = 194)

From: Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study

Variables Coefficient B SEM Wald P value OR Exp(B) OR 95% CI
Lower Upper
Individual characteristics
 Age of 1st depression −0.051 0.025 4.003 0.045 0.951 0.905 0.999
 Marital status 1.583 0.701 5.108 0.024 4.872 1.234 19.235
 First degree relatives with affective disorders 0.262 0.593 0.195 0.659 1.299 0.406 4.157
 More than one hospitalization for depression −2.148 0.614 12.239 0.001 0.177 0.035 0.389
 Psychotherapy treatment −2.232 0.699 10.190 0.001 0.107 0.027 0.423
 History of suicide attempt −0.135 0.625 0.047 0.829 0.874 0.257 2.974
Comorbidities
 Current anxiety disorders 2.357 0.608 15.033 0.001 10.560 3.208 34.763
Severity of depression
 Melancholic depressive features 0.650 0.747 0.755 0.385 1.915 0.422 8.285
 Failed pharmacotherapies 0.266 0.106 6.331 0.012 1.304 1.060 1.604
 HAM-D17 score −0.193 0.067 8.208 0.004 0.824 0.722 0.941
Level of functioning
 Global assessment of functioning score (GAF) 0.164 0.047 11.985 0.001 1.178 1.074 1.293
  1. TRD-UP Treatment-Resistant Unipolar Depression, BP Bipolar disorder type I and type II, OR Odds ratio, CI Confidence interval, SEM Standard Error of Mean. Boldface indicates significant association at an alpha level = 0.01