The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment

Table 3 Mean age (SD) and mean levels (SD) of peripheral circulating cytokines in healthy volunteers and a subgroup of matched patients

Variable		Matched patients	Healthy volunteers	Sig.^a
Variable		n = 19	n = 19
Age	(years)	42.5 (7.9)	28.8 (5.4)	<0.001 ^b
Il-1β	(picograms/ml)	0.15 (0.31)	0.13 (0.19)	0.740
Il-1RA	(picograms/ml)	36.3 (33.0)	35.4 (19.5)	0.385
TNF-α	(picograms/ml)	2.67 (6.67)	0.82 (2.75)	< 0.001 ^c
MCP-1	(picograms/ml)	26.8 (21.4)	15.8 (15.5)	0.012 ^d

Note: ^aSignificance levels were tested by the Mann-Whitney U test. ^bPatients were older than the healthy volunteers. ^c⁺^d Levels of TNF-α and MCP-1 were higher in patients
Both healthy volunteers and matched patients were male

ISSN: 1471-244X