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Table 1 Demographic, clinical and medication information of bipolar patients and healthy controls

From: Differential mitochondrial DNA copy number in three mood states of bipolar disorder

  Bipolar patients Health control Statistic
Manic
N = 55
Depression N = 47 Euthymic N = 29 N = 34  
Age, mean (SD) 26.67 (7.15) 26.94 (8.91) 23.76 (3.94) 24.50 (3.82) ANOVA, F = 2.05, P = 0.108
Sex
 Male 26 23 9 19  
 Female 23 24 20 15 df = 3, X2 = 4.13, P = 0.25
Years of education, mean (SD) 12.55 (2.80) 12.38 (3.47) 12.24 (2.52) 13.56 (2.78) ANOVA, F = 1.41, P = 0.13
 BMI, mean(SD) 21.63 (1.89) 21.45 (1.78) 21.93 (1.69) 21.5 (1.40) ANOVA, F = 1.63, P = 0.18
Medication information  
 Antipsychotics 51/55 37/47 23/29   df = 2, X2 = 4.69, P = 0.09
Anticonvulsants 24/55 21/47 18/29   df = 2, X2 = 2.92, P = 0.23
 CPZ equivalents, mean(SD) 241.58 (93.43) 224.55 (79.90) 227.31 (64.16)   ANOVA, F = 0.519, P = 0.67
Benzodiazepines 15/55 17/47 5/29   df = 2, X2 = 3.22, P = 0.20
 Lithium 22/55 19/47 12/29   df = 2, X2 = 4.72, P = 0.094
Clinical characteristics Man vs Eut Dep vs Eut Man vs Dep
 Duration of illness, months, mean (SD) 70.91(59.24) 67.70 (61.91) 47.45 (34.66)   P = 0.140 P = 0.361 P = 1
YMRS, mean(SD) 33.78 (6.08) 8.19 (7.31) 2.78 (2.24)   P < 0.001 P < 0.001 P < 0.001
 HDRS, mean(SD) 6.90 (8.24) 27.89 (6.61) 2.63 (3.18)   P < 0.001 P < 0.001 P < 0.001
Number of Previous Episodes, mean (SD) 3.55 (1.74) 3.60 (1.70) 2.90 (2.28)   P = 0.713 P = 0.654 P = 1
 MtDNAcn, Median (range) 1.59 (1.31,2.07) 1.83 (1.22,2.31) 2.05 (1.5,2.96) 2.38 (1.77,3.24)    
  1. Abbreviations: BMI body mass index, SD standard deviation, YMRS young mania rating scale. HDRS hamilton depression rating scale, ANOVA one-way analysis of variance, Man manic, Dep depression, Eut euthymic