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Table 2 Comparisons of HDL-cholesterol levels in the three antipsychotic groups with stratification by BMI for inpatients

From: High-density lipoprotein-cholesterol and antipsychotic medication in overweight inpatients with schizophrenia: post-hoc analysis of a Japanese nationwide survey

 

Olanzapine

Risperidone

Aripiprazole

p-value

Post-hoc (p-value)

HDL-cholesterol

BMI < 18.5

mg/dL

62.0 ± 20.5 (34)

58.6 ± 15.8 (55)

62.6 ± 21.6 (28)

0.490

 

18.5 ≤ BMI < 25

mg/dL

54.1 ± 21.5 (137)

55.0 ± 16.2 (196)

58.2 ± 15.8 (68)

0.282

 

BMI ≥ 25

mg/dL

43.8 ± 12.3 (47)

49.7 ± 15.0 (84)

54.7 ± 16.8 (25)

0.019

Olanzapine < Aripiprazole (0.023)

  1. Data are shown as the mean ± SD (number of subjects)
  2. Analyses of covariance among the three antipsychotics were performed for HDL-cholesterol with age, diastolic blood pressure, chlorpromazine-equivalent dosage and waist circumference as confounding variables
  3. Post-hoc analyses were performed by the Bonferroni method
  4. HDL high-density lipoprotein, BMI body mass index