Table 3 Association between use of acetaminophen by mother during pregnancy and mental health outcomes at the age of 6 years among boys (N = 1812) and girls (N = 1658)
Outcomes | Frequency of outcome according to use of acetaminophen during pregnancy N (%) | Crude analysis | Adjusted analysisa | ||
|---|---|---|---|---|---|
Exposed n (%) | Not exposed n (%) | OR (95% CI) | OR (95% CI) | p b | |
Boys | |||||
Total SDQ (score ≥ 17 pts) | 63 (12.00) | 149 (11.58) | 1.04 (0.76–1.43) | 1.28 (0.90–1.83) | 0.163 |
Emotional symptoms (score ≥ 5 pts) | 83 (15.81) | 154 (11.97) | 1.38 (1.04–1.84) | 1.47 (1.07–2.02) | 0.018 |
Conduct problems (score ≥ 4 pts) | 72 (13.71) | 223 (17.33) | 0.76 (0.57–1.02) | 0.93 (0.68–1.27) | 0.641 |
Hyperactivity/inattention (score ≥ 7 pts) | 93 (17.71) | 195 (15.15) | 1.21 (0.92–1.58) | 1.42 (1.06–1.92) | 0.020 |
Peer relationship problems (score ≥ 4 pts) | 81 (15.43) | 196 (15.23) | 1.02 (0.77–1.35) | 1.25 (0.91–1.71) | 0.167 |
Prosocial behavior (score ≤ 4 pts) | 5 (0.95) | 18 (1.40) | 0.68 (0.25–1.84) | 0.60 (0.19–1.88) | 0.376 |
Girls | |||||
Total SDQ (score ≥ 17 pts) | 39 (8.86) | 122 (10.02) | 0.87 (0.60–1.28) | 1.02 (0.67–1.54) | 0.943 |
Emotional symptoms (score ≥ 5 pts) | 54 (12.27) | 181 (14.86) | 0.80 (0.58–1.11) | 0.90 (0.63–1.28) | 0.557 |
Conduct problems (score ≥ 4 pts) | 47 (10.68) | 173 (14.20) | 0.72 (0.51–1.02) | 0.79 (0.54–1.16) | 0.226 |
Hyperactivity/inattention (score ≥ 7 pts) | 44 (10.00) | 149 (12.23) | 0.80 (0.56–1.14) | 0.76 (0.51–1.12) | 0.165 |
Peer relationship problems (score ≥ 4 pts) | 43 (9.77) | 170 (13.96) | 0.67 (0.47–0.95) | 0.88 (0.59–1.31) | 0.535 |
Prosocial behavior (score ≤ 4 pts) | 3 (0.68) | 15 (1.23) | 0.55 (0.16–1.91) | 0.73 (0.20–2.69) | 0.630 |