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Table 1 Characteristics of the study population (n = 402) according to stratification of season and post-stroke depression

From: Impact of seasons on stroke-related depression, mediated by vitamin D status

 

Stratification of season

 

Post-stroke depression

 

Wintertime (n = 265)

Summertime (n = 137)

P-value

Non-PSD (n = 295)

PSD (n = 107)

P-value

Demographic characteristics

 Age (years), mean ± SD

62.47 ± 10.22

62.29 ± 10.31

0.871

62.85 ± 10.29

61.18 ± 10.04

0.149

 Female, n (percent)

86 (32.5)

46 (33.6)

0.82

94 (31.9)

38 (35.5)

0.491

 BMI (kgm−2), mean ± SD

24.00 ± 3.28

23.97 ± 3.29

0.899

23.84 ± 3.18

24.42 ± 2.94

0.1

 Education (years), median (IQR)

5 (0–7)

4.5 (1–7)

0.889

4.5 (0–7)

5 (0–7)

0.862

Vascular risk factors (%)

 Hypertension

192 (72.7)

101 (73.7)

0.831

211 (71.8)

82 (76.6)

0.331

 Diabetes mellitus

55 (20.9)

46 (33.6)

0.006

76 (25.9)

25 (23.4)

0.6

 Hyperlipidemia

18 (6.9)

6 (4.4)

0.316

14 (4.8)

10 (9.4)

0.086

 Coronary heart disease

19 (7.3)

4 (2.9)

0.076

20 (6.9)

3 (2.9)

0.136

 History of stroke

23 (8.8)

20 (14.6)

0.075

32 (10.9)

11 (10.4)

0.877

 Active smokers

82 (31.5)

37 (27.6)

0.421

93 (32.2)

26 (24.8)

0.156

 Alcohol consumption

94 (37.3)

46 (35.9)

0.794

111 (39.8)

29 (28.7)

0.048

Systolic blood pressure (mmHg), mean ± SD

153.68 ± 21.38

158.45 ± 24.54

0.055

154.78 ± 22.91

156.76 ± 21.72

0.439

Diastolic blood pressure (mmHg), mean ± SD

82.96 ± 13.16

85.34 ± 13.03

0.085

83.40 ± 13.34

84.79 ± 12.63

0.149

Stroke subtype

  

0.629

  

0.001

 Hemorrhagic stroke

47 (17.7)

27 (19.7)

 

43 (14.6)

31 (29.0)

 

 Ischemia stroke

218 (82.3)

110 (80.3)

 

252 (85.4)

76 (71.0)

 

NIHSS score

3 (1–4)

3 (1–4)

0.909

2 (1–4)

3 (2–6)

< 0.001

Vitamin D (nmol/L), median (IQR)

46.98 (30.90–57.88)

52.44 (46.04–68.11)

< 0.001

51.06 (36.44–63.95)

43.80 (30.40–55.88)

0.011

HAMD at 1 month, median (IQR)

5 (2–9)

3 (2–6.5)

0.005

3 (1–5)

10 (9–13)

< 0.001

  1. Values are shown as number (percentage) or as medians (IQR) and means (±SD)
  2. PSD post-stroke depression, SD standard deviation, IQR interquartile range, BMI body mass index, NIHSS National Institutes of Health Stroke Scale, HAMD Hamilton Rating Scale for Depression