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Table 2 Results of the gender and cancer factors two-way ANOVA of the 18F-FDG PET brain image

From: Gender-disease interaction on brain cerebral metabolism in cancer patients with depressive symptoms

Two-way ANOVA Cluster size Anatomical region Hemisphere BA F-value Peak coordinates(x,y,z)(mm)
Cancer main effect 2030 Frontal_sup Left 6 13.2 −21 -12 63
1551 Parietal_sup Right 40 11.59 33 –63 52
1066 Supp_motor_area Left 6 12.46 −7 8 74
374 Frontal_mid_orb Left 10.55 −33 47 –8
317 Frontal_mid Right 40 11.59 33 –63 52
143 Cingulum_mid Left 5 8.95 −7 -39 51
141 Parietal_inf Left 40 8.7 38 –57 54
138 Frontal_sup_medical Left 8 9.33 −7 46 50
Gender main effect 21,928 Cerebellum posterior lobe Right 23.41 22 –68 -30
20,683 Cerebellum posterior lobe Left 19.01 −17 -67 -32
1195 Temporal_inf Left 20 11.63 −44 -51 -14
1100 Cuneus Right 7 11.91 11 –76 42
495 Cingulum_mid Left 24 10.37 −10 -6 39
378 Precentral Left 6 10.54 −21 -11 62
127 Frontal_sup Right 6 9.53 20 –14 70
Interaction 356 Frontal_sup Left 6 16.44 −20 -12 61
305 Precuneus Left 7 14.67 −4 -76 43
233 Postcentral Right 4 16.33 28 –29 59
209 Frontal_sup Right 6 17.40 19 –14 70
  1. For each significant cluster, we reported the F-value (peak intensity) and MNI coordinates at the position of the maximum, the cluster size (k) and the corresponding Brodmann area (BA). Only clusters with k > 100 are shown