Table 5 Estimated marginal means (EMM) of the outcomes
Outcome |  | ZemCAD (n = 70) | Control (n = 71) |
|---|---|---|---|
EMM (SEMa) | EMM (SEM) | ||
Quality of life (WHOQOL-BREFb) | |||
 Total score | Baseline | 73.31 (1.73) | 72.38 (1.75) |
6 months (T1) | 74.89 (1.74) | 73.27 (1.79) | |
12 months (T2) | 78.21 (1.78) | 73.39 (1.82) | |
18 months (T3) | 77.36 (1.79) | 74.54 (1.82) | |
 Domain 1; | Baseline | 18.13 (0.57) | 17.86 (0.58) |
 Physical health | 6 months (T1) | 18.79 (0.58) | 18.11 (0.60) |
12 months (T2) | 20.40 (0.60) | 18.30 (0.61) | |
18 months (T3) | 20.02 (0.61) | 19.07 (0.61) | |
 Domain 2; | Baseline | 15.31 (0.43) | 15.40 (0.43) |
 Psychological | 6 months (T1) | 15.80 (0.43) | 15.41 (0.45) |
12 months (T2) | 16.37 (0.45) | 15.60 (0.46) | |
18 months (T3) | 16.34 (0.45) | 15.62 (0.46) | |
 Domain 3; | Baseline | 8.23 (0.29) | 8.62 (0.29) |
 Social relationships | 6 months (T1) | 8.55 (0.29) | 8.77 (0.30) |
12 months (T2) | 8.70 (0.30) | 8.36 (0.31) | |
18 months (T3) | 8.66 (0.31) | 8.60 (0.31) | |
 Domain 4; | Baseline | 26.56 (0.61) | 25.60 (0.61) |
 Environment | 6 months (T1) | 26.67 (0.61) | 26.09 (0.63) |
12 months (T2) | 27.39 (0.63) | 26.45 (0.64) | |
18 months (T3) | 27.15 (0.63) | 26.21 (0.64) | |
Anxiety (BAIc) | |||
 Total score | Baseline | 43.76 (1.50) | 45.42 (1.52) |
6 months (T1) | 43.88 (1.52) | 44.66 (1.56) | |
12 months (T2) | 40.88 (1.56) | 43.84 (1.61) | |
18 months (T3) | 42.53 (1.58) | 44.46 (1.60) | |
Depression (PHQ-9d) | |||
 Total score | Baseline | 22.46 (0.77) | 23.33 (0.78) |
6 months (T1) | 21.16 (0.78) | 21.93 (0.80) | |
12 months (T2) | 19.86 (0.80) | 20.63 (0.83) | |
18 months (T3) | 21.27 (0.82) | 20.99 (0.83) | |
Empowerment (NELe) | |||
 Total score | Baseline | 121.94 (2.35) | 121.37 (2.38) |
6 months (T1) | 125.58 (2.38) | 119.59 (2.45) | |
12 months (T2) | 126.88 (2.44) | 119.92 (2.50) | |
18 months (T3) | 123.66 (2.47) | 123.08 (2.50) | |
 Dimension 1; | Baseline | 13.40 (0.57) | 13.80 (0.58) |
 Professional help | 6 months (T1) | 13.65 (0.59) | 12.78 (0.61) |
12 months (T2) | 12.28 (0.62) | 12.16 (0.63) | |
18 months (T3) | 9.39 (0.63) | 12.23 (0.63) | |
 Dimension 2; | Baseline | 23.03 (0.58) | 23.78 (0.59) |
 Social support | 6 months (T1) | 23.55 (0.59) | 23.52 (0.61) |
12 months (T2) | 24.10 (0.61) | 23.77 (0.62) | |
18 months (T3) | 23.99 (0.61) | 23.47 (0.62) | |
 Dimension 3; | Baseline | 34.98 (0.93) | 34.29 (0.94) |
 Confidence and purpose | 6 months (T1) | 36.77 (0.94) | 34.20 (0.96) |
12 months (T2) | 37.63 (0.96) | 34.86 (0.99) | |
18 months (T3) | 37.68 (0.97) | 36.19 (0.99) | |
 Dimension 4; | Baseline | 18.65 (0.46) | 18.20 (0.47) |
 Connectedness | 6 months (T1) | 19.41 (0.47) | 17.77 (0.48) |
12 months (T2) | 19.42 (0.49) | 18.26 (0.50) | |
18 months (T3) | 19.27 (0.49) | 18.94 (0.50) | |
 Dimension 5; | Baseline | 15.22 (0.37) | 15.53 (0.38) |
 Self-management | 6 months (T1) | 15.48 (0.38) | 15.72 (0.39) |
12 months (T2) | 16.15 (0.39) | 15.48 (0.40) | |
18 months (T3) | 16.20 (0.40) | 16.03 (0.40) | |
 Dimension 6; | Baseline | 16.66 (0.47) | 15.79 (0.47) |
 Caring community | 6 months (T1) | 16.84 (0.48) | 15.67 (0.49) |
12 months (T2) | 17.51 (0.49) | 15.45 (0.50) | |
18 months (T3) | 17.29 (0.50) | 16.27 (0.50) | |