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Table 1 Clinical and sociodemographic characteristics of patients

From: Predictors of the effectiveness of an early medication change strategy in patients with major depressive disorder

Characteristic EMC (n = 97) TAU (n = 95) p-value
Patient characteristics
 Age (mean +/− SD) 39.4 ± 11.5 38.9 ± 12.2 0.796
 Female sex – n (%) 55 (57) 52 (55) 0.784
Symptom-based subtypes - n (%)
 Melancholic MDD 78 (80) 81 (85) 0.721
 Atypical MDD 36 (37) 35 (37) 0.881
 Anxious MDD 65 (67) 67 (71) 0.762
 MDD with suicidality 80 (84) 75 (79) 0.389
 1st episode - n (%) 30 (31) 31 (33) 0.924
Severity of depression (IDS-C30)
 Mean IDS-C30 score (mean +/− SD) 44.2 ± 8.7 45.3 ± 8.4 0.352
 Mean IDS-SR30 score (mean +/− SD) 45.5 ± 10.3 45.5 ± 10.1 0.958
 Axis I - n (%) 52 (54) 52 (55) 0.996
 Axis II - n (%) 42 (43) 37 (39) 0.554
Physical comorbidities CIRS
 Total severity score ((mean +/− SD) 1.9 ± 2.1 1.7 ± 1.9 0.506
 Cardiac 0.1 ± 0.4 0.1 ± 0.1 0.460
 Hypertension 0.02 ± 0.1 0.02 ± 0.1 0.983
 Vascular 0.2 ± 0.5 0.3 ± 0.6 0.136
 Respiratory 0.4 ± 0.7 0.3 ± 0.6 0.339
 ENT 0.1 ± 0.3 0.1 ± 0.5 0.402
 Upper GI 0.1 ± 0.4 0.1 ± 0.1 0.470
 Lower GI 0.1 ± 0.3 0.2 ± 0.5 0.195
 Hepatic 0.01 ± 0.1 0.02 ± 0.2 0.645
 Renal 0.1 ± 0.3 0.1 ± 0.4 0.543
 Musculo-sceletal-integumentary 0.4 ± 0.9 0.3 ± 0.6 0.275
 Neurological 2.1 ± 1.2 2.4 ± 1.4 0.334
 Endocrine-metabolic 0.2 ± 0.5 0.2 ± 0.5 0.208
 Psychiatric somatic symptoms (HAMD-17 item 11) 1.6 ± 1.0 1.8 ± 1.0 0.104
  1. SD Standard deviation, EMC Early Medication Change, TAU Treatment as Usual, MDD Major Depressive Disorder, IDS-30 30-item Quick Inventory of Depressive Symptomatology, C Clinician–Rated, SR Self-Rating, CIRS Clinical incident rating scale, without the psychiatric somatic symptoms; Data concerning age, gender, 1st episode/recurrent MDD, severity of depression, psychiatric and physical comorbidities were published before in [18].