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Table 3 Haplotype-based association analyses between rs1344706 and rs7603001 in ZNF804A in 640 Han Chinese autism trios

From: Family-based association study of ZNF804A polymorphisms and autism in a Han Chinese population

Marker Haplotype Freq Fam S-E(S) Var(S) Z P Global P Ppermutationa
rs7603001-rs1344706 G-C 0.414 212 15.92 72.89 1.864 0.062 0.100 0.089
A-A 0.305 285 −14.08 83.76 −1.539 0.124   
G-A 0.276 207 −0.42 65.90 −0.051 0.959   
A-C 0.006 4 n/a n/a n/a n/a   
  1. Abbreviations: Freq, Estimation of haplotype frequencies; Fam, number of informative families; S, test statistics for the observed number of transmitted alleles; E(S), expected value of S under the null hypothesis (i.e., no linkage and no association); n/a: not applicable
  2. a Whole marker permutation test was performed using chisq sum P value (n = 10,000)