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Table 1 Socio-demographic and clinical characteristics and psychotropic drug prescription in urban and rural areas a

From: Psychotropic medication treatment patterns in community-dwelling schizophrenia in China: comparisons between rural and urban areas

 

Total

(N = 993)

Urban

(N = 514)

Rural

(N = 479)

X2

df

P

n

%

n

%

n

%

Male gender

586

59.0

273

53.1

313

65.3

15.3

1

< 0.001

Married

393

39.6

182

35.4

211

44.1

7.7

1

0.005

Employed

661

66.6

342

66.5

319

66.6

0

1

0.98

First episode

219

22.1

163

31.7

56

11.7

57.8

1

< 0.001

Personal income over 3000 yuan

24

2.4

19

3.7

5

1.0

7.3

1

0.007

No health insurance

126

12.7

122

23.7

4

0.8

117.3

1

< 0.001

Psychiatric family history

195

19.6

137

26.7

58

12.1

25.6

1

< 0.001

Major medical conditions

231

23.3

201

39.1

30

6.3

149.8

1

< 0.001

Clozapine

357

36.0

222

43.2

135

28.2

24.2

1

< 0.001

FGA

431

43.4

231

44.9

200

41.8

1.02

1

0.31

SGA except Clozapine

411

41.4

161

31.3

250

52.2

44.5

1

< 0.001

APP

310

31.2

193

37.5

117

24.4

19.8

1

< 0.001

Antidepressants

40

4.0

28

5.4

12

2.5

5.5

1

0.01

Mood stabilizers

189

19.0

108

21.0

81

16.9

2.7

1

0.1

Benzodiazepine

161

16.2

128

24.9

33

6.9

59.2

1

< 0.001

Anticholinergics

432

43.5

187

36.4

245

51.1

21.9

1

< 0.001

 

Mean

SD

Mean

SD

Mean

SD

t/u

df

P/Z

Age,y

43.2

11.6

46.8

10.2

39.4

11.8

10.6

991

< 0.001

Education,y

9.4

2.7

10.5

2.8

8.3

2.2

13.3

991

< 0.001

Age of onset,y

25.6

9.1

25.1

8.9

26.0

9.3

−1.6

991

0.103

Illness duration,y

17.6

11.1

21.7

10.3

13.3

10.1

12.8

991

< 0.001

No. Of admissions

2.2

2.4

2.4

2.7

2.1

2.03

−1.1

...

0.26b

BMI,kg/m2

23.6

4.1

24.7

4.8

22.5

2.4

8.7

985

< 0.001

PDD/DDD

0.9

1.2

0.9

1.6

0.8

0.5

1.7

991

0.08

MADRS total score

7.4

8.2

10.01

9.3

4.7

5.7

10.6

991

< 0.001

BPRS score

 positive

5.9

2.8

6.1

3.1

5.8

2.4

1.9

991

0.053

 negative

5.7

2.8

6.2

3.08

5.3

2.5

4.8

991

< 0.001

 anxiety

4.2

2.03

3.2

1.7

5.2

1.8

−18.2

991

< 0.001

SAS total score

11.7

4.2

5.2

0.2

2.2

0.1

9.8

991

< 0.001

  1. Abbreviations: APP antipsychotic polypharmacy, BMI body mass index, BPRS brief psychiatric rating scale, FGA first-generation antipsychotic, MADRS Montgomery-Asberg Depression Rating Scale, PDD/DDD prescribed daily dose/the defined daily dose ratio, SAS Simpson and Angus scale of extrapyramidal symptoms, SGA second-generation antipsychotic
  2. a Boldface indicates a statistically significant difference (P < 0.05)
  3. b Mann-Whitney U test was used