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Table 2 Single site association analysis result of seven single-nucleotide polymorphisms in case-control samples of Uygur population

From: SLC39A8 is a risk factor for schizophrenia in Uygur Chinese: a case-control study

SNP Allele frequency OR [95%CI] Chi2 P-value Corrected p Power Genotypes frequency Chi2 P value Corrected
p
Rs233814 C T        C/T T/T C/C    
Cases 1276 (0.651) 682 (0.348)   0.968 [0.855~1.096] 0.255 0.613   0.223 420 (0.429) 131 (0.133) 428 (0.437) 2.867 0.249  
Control 1580 (0.643) 872 (0.356)        570 (0.464) 151 (0.123) 505 (0.411)    
Rs233820 C G A       C/G G/G A/A    
Cases 739 (0.376) 1142 (0.582) 81 (0.041) NA [NA~NA] 1.09 0.579   NA 429 (0.437) 330 (0.336) 1 (0.001) 1.194 0.956  
          C/A C/C G/A    
          26 (0.026) 142 (0.144) 53 (0.054)    
Control 927 (0.38) 1427 (0.583) 86 (0.035)       C/G G/G A/A    
          543 (0.445) 413 (0.338) 1 (8.2e-04)    
          C/A C/C G/A    
          26 (0.021) 179 (0.146) 58 (0.047)    
Rs10014145 A G        A/A G/G G/A    
Cases 1436 (0.758) 458 (0.241)   1.196 [1.036~1.382] 5.999 0.014* 0.098 0.999 540 (0.57) 51 (0.053) 356 (0.375) 10.666 0.004* 0.032*
Control 1895 (0.789) 505 (0.21)        762 (0.635) 67 (0.055) 371 (0.309)    
Rs4698844 C T        C/C C/T T/T    
Cases 1295 (0.663) 657 (0.336)   0.929 [0.819~1.053] 1.284 0.249   0.663 441 (0.451) 413 (0.423) 122 (0.125) 2.999 0.223  
Control 1586 (0.646) 866 (0.353)        512 (0.417) 562 (0.458) 152 (0.123)    
Rs151394 G C        G/G C/G C/C    
Cases 712 (0.365) 1236 (0.634)   0.946 [0.836~1.071] 0.756 0.384   0.454 143 (0.146) 426 (0.437) 405 (0.415) 3.071 0.215  
Control 917 (0.378) 1507 (0.621)        171 (0.141) 575 (0.474) 466 (0.384)    
Rs985989 C A        C/A A/A C/C    
Cases 1040 (0.533) 910 (0.466)   0.936 [0.831~1.055] 1.146 0.284   0.523 496 (0.508) 207 (0.212) 272 (0.278) 1.308 0.519  
Control 1244 (0.517) 1162 (0.482)        604 (0.502) 279 (0.231) 320 (0.266)    
Rs13114343 G A        G/G A/A G/A    
Cases 1005 (0.514) 949 (0.485)   1.091 [0.968~1.23] 2.08 0.149   0.884 260 (0.266) 232 (0.237) 485 (0.496) 2.179 0.336  
Control 1303 (0.536) 1127 (0.463)        356 (0.293) 268 (0.22) 591 (0.486)    
  1. Abbreviations: OR odds ratio, CI confidence interval
  2. Significant P values were corrected using Bonferroni correction (multiplied by the number of testing SNPs).* P values< 0.05