Table 2 Single site association analysis result of seven single-nucleotide polymorphisms in case-control samples of Uygur population
From: SLC39A8 is a risk factor for schizophrenia in Uygur Chinese: a case-control study
SNP | Allele frequency | OR [95%CI] | Chi2 | P-value | Corrected p | Power | Genotypes frequency | Chi2 | P value | Corrected p | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rs233814 | C | T | C/T | T/T | C/C | |||||||||
Cases | 1276 (0.651) | 682 (0.348) | 0.968 [0.855~1.096] | 0.255 | 0.613 | 0.223 | 420 (0.429) | 131 (0.133) | 428 (0.437) | 2.867 | 0.249 | |||
Control | 1580 (0.643) | 872 (0.356) | 570 (0.464) | 151 (0.123) | 505 (0.411) | |||||||||
Rs233820 | C | G | A | C/G | G/G | A/A | ||||||||
Cases | 739 (0.376) | 1142 (0.582) | 81 (0.041) | NA [NA~NA] | 1.09 | 0.579 | NA | 429 (0.437) | 330 (0.336) | 1 (0.001) | 1.194 | 0.956 | ||
C/A | C/C | G/A | ||||||||||||
26 (0.026) | 142 (0.144) | 53 (0.054) | ||||||||||||
Control | 927 (0.38) | 1427 (0.583) | 86 (0.035) | C/G | G/G | A/A | ||||||||
543 (0.445) | 413 (0.338) | 1 (8.2e-04) | ||||||||||||
C/A | C/C | G/A | ||||||||||||
26 (0.021) | 179 (0.146) | 58 (0.047) | ||||||||||||
Rs10014145 | A | G | A/A | G/G | G/A | |||||||||
Cases | 1436 (0.758) | 458 (0.241) | 1.196 [1.036~1.382] | 5.999 | 0.014* | 0.098 | 0.999 | 540 (0.57) | 51 (0.053) | 356 (0.375) | 10.666 | 0.004* | 0.032* | |
Control | 1895 (0.789) | 505 (0.21) | 762 (0.635) | 67 (0.055) | 371 (0.309) | |||||||||
Rs4698844 | C | T | C/C | C/T | T/T | |||||||||
Cases | 1295 (0.663) | 657 (0.336) | 0.929 [0.819~1.053] | 1.284 | 0.249 | 0.663 | 441 (0.451) | 413 (0.423) | 122 (0.125) | 2.999 | 0.223 | |||
Control | 1586 (0.646) | 866 (0.353) | 512 (0.417) | 562 (0.458) | 152 (0.123) | |||||||||
Rs151394 | G | C | G/G | C/G | C/C | |||||||||
Cases | 712 (0.365) | 1236 (0.634) | 0.946 [0.836~1.071] | 0.756 | 0.384 | 0.454 | 143 (0.146) | 426 (0.437) | 405 (0.415) | 3.071 | 0.215 | |||
Control | 917 (0.378) | 1507 (0.621) | 171 (0.141) | 575 (0.474) | 466 (0.384) | |||||||||
Rs985989 | C | A | C/A | A/A | C/C | |||||||||
Cases | 1040 (0.533) | 910 (0.466) | 0.936 [0.831~1.055] | 1.146 | 0.284 | 0.523 | 496 (0.508) | 207 (0.212) | 272 (0.278) | 1.308 | 0.519 | |||
Control | 1244 (0.517) | 1162 (0.482) | 604 (0.502) | 279 (0.231) | 320 (0.266) | |||||||||
Rs13114343 | G | A | G/G | A/A | G/A | |||||||||
Cases | 1005 (0.514) | 949 (0.485) | 1.091 [0.968~1.23] | 2.08 | 0.149 | 0.884 | 260 (0.266) | 232 (0.237) | 485 (0.496) | 2.179 | 0.336 | |||
Control | 1303 (0.536) | 1127 (0.463) | 356 (0.293) | 268 (0.22) | 591 (0.486) | |||||||||