The association of genetic polymorphisms in CYP1A2, UGT1A4, and ABCB1 with autonomic nervous system dysfunction in schizophrenia patients treated with olanzapine

Table 1 CYP1A2, UGT1A4, and ABCB1 single nucleotide polymorphisms (SNPs)

Gene	SNP	Location	Alleles	Frequency (Global)	Frequency (Japanese)
CYP1A2	rs2069514	Chr.15: 74745879	G/A	0.209	0.236
CYP1A2	rs762551	Chr.15: 74749576	C/A	0.630	0.636
UGT1A4	rs2011425	Chr.2: 233718962	T/G	0.116	0.127
ABCB1	rs1045642	Chr.7: 87509329	C/T	0.503	0.577
	rs1128503	Chr.7: 87550285	C/T	0.542	0.384
	rs2032582	Chr.7: 87531302	G/A or T	0.543	0.422
	rs2235048	Chr.7: 87509195	T/C	0.602	0.585

Data from TogoVar [Internet]. Tokyo: Japan Science and Technology Agency (Japan), National Bioscience Database Center; 2020. Available from https://togovar.biosciencedbc.jp

ISSN: 1471-244X