Dimensions of leisure-time physical activity and risk of depression in the “Seguimiento Universidad de Navarra” (SUN) prospective cohort

Table 2 Depression risk according to different dimensions of baseline physical activity. The SUN Project 1999–2018

Totalleisure-timephysical activity (MET-h/wk)	< 10MET-h/wk	10 to 20MET-h/wk	> 20MET-h/wk	P for trend
Depression cases / person-years	366/59193	193/37606	311/66260	0.046
Multivariable-adjusted HR ^a (95% CI)	1 (ref.)	0.88 (0.74–1.05)	0.84 (0.72–0.99)	0.046
Time spent in leisure time physical activity (hours/wk)	< 75 min/wk	75–300 min/wk	> 300 min/wk	0.057
Events / person-years	279/44420	345/65624	246/53015
Multivariable-adjusted HR ^b (95% CI)	1 (ref.)	0.88 (0.75–1.04)	0.83 (0.70–0.99)
Intensity in leisure time physical activity (average METS)	Inactive	< 6 Average METs	≥ 6 Average METs	0.650
Events / person-years	161/26004	574/110834	135/26220
Multivariable-adjusted HR ^c (95% CI)	1 (ref.)	0.90 (0.75-1.09)	1.00 (0.79-1.27)

^a Adjusted for sex, baseline body mass index, time sleeping, time nap, time TV, total energy intake, adherence to the Mediterranean Diet, alcohol intake, smoking pack years, educational level, hypertension, diabetes mellitus, cancer and changes in physical activity in the 2th and 4th year follow-up, with age and year of entering the cohort as stratification variables
^b Additional adjusted by intensity physical activity
^c Additional adjusted by leisure time physical activity

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