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Table 5 Association between baseline patient characteristics, symptom scores, complexity scores, and clinician’s assessment(a, b), and treatment response, defined as achievement of a 5 point reduction in PHQ-9 score at last attended visit up to the 5th treatment visit, and drop out form the service, defined as failure to return for treatment after the initial assessment visit. Data analysed using univariate and multivariable logistic regression models. Results presented as odds ratios, with 95% confidence intervals and p-values. Best-fitting multivariable models found by backward selection from all predictors

From: Clinical judgement, case complexity and symptom scores as predictors of outcome in depression: an exploratory analysis

Predictor

Effect

Drop out from service

Achievement of 5 point reduction in PHQ-9

Univariable

Multivariable

Univariate

Multivariable

OR (95% CI), p-value

OR (95% CI), p-value

OR (95% CI), p-value

OR (95% CI), p-value

Age

per 10 years

1.03 (0.85, 1.26), p = 0.756

 

0.72 (0.54, 0.94), p = 0.017

0.71 (0.52, 0.95), p = 0.022

Gender

Female vs. Male

0.62 (0.37, 1.03), p = 0.066

 

0.81 (0.41, 1.6), p = 0.555

 

Current Smoker

Yes vs. No

2.34 (1.31, 4.22), p = 0.004

2.49 (1.3, 4.81), p = 0.006

2.65 (1.06, 7.6), p = 0.048

 

Current AD Use

Yes vs. No

1.09 (0.66, 1.81), p = 0.742

 

1.47 (0.77, 2.81), p = 0.239

 

Prev Prob Count

per problem

1.02 (0.92, 1.14), p = 0.701

 

1.13 (0.97, 1.32), p = 0.131

 

Curr Prob Count

per problem

0.94 (0.82, 1.06), p = 0.299

 

1.02 (0.87, 1.2), p = 0.82

 

MECAM

per point

0.97 (0.93, 1.02), p = 0.275

0.93 (0.88, 0.98), p = 0.01

1.03 (0.97, 1.1), p = 0.333

 

PHQ-9

per point

1 (0.95, 1.04), p = 0.953

 

1.13 (1.07, 1.21), p < 0.001

1.13 (1.07, 1.21), p < 0.001

GAD

per point

0.96 (0.91, 1.01), p = 0.131

 

1.17 (1.09, 1.27), p < 0.001

 

CORE-10

per point

0.98 (0.94, 1.02), p = 0.416

 

1.09 (1.04, 1.16), p = 0.002

 

Clinician assessment(a)

No vs. Yes

7.8 (3.03, 24.13), p < 0.001

8.59 (3.16, 27.94), p < 0.001

 

Clinician assessment(b)

Yes vs. No

 

1.09 (0.47, 2.43), p = 0.838