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Table 3 Antipsychotic polypharmacy combinations by treatment family in patients diagnosed with schizophrenia: 2008–2015

From: Epidemiology of schizophrenia and its management over 8-years period using real-world data in Spain

Polypharmacy combinations

N (% of total)

Subjects %

Time %

OA-2nd generation

18,241 (27.5)

38.1

16.2

OA-2nd generation + LAI-2nd generation

16,188 (24.4)

26.0

12.7

OA-1st generation + OA-2nd generation

10,271 (15.5)

21.1

7.9

OA-1st generation + OA-2nd generation + LAI-2nd generation

4213 (6.3)

7.5

2.4

Othera + OA-2nd generation

3899 (5.9)

7.9

3.1

LAI-1st generation + OA-2nd generation

3325 (5.0)

7.6

3.1

Other combinations

10,281 (15.5)

31.8

6.3

  1. Abbreviations: OA Oral antipsychotic, LAI Long-acting injection antipsychotics
  2. aOther family treatments different to OA and LAI
  3. Subjects (%), percentage of subjects ever treated with each polypharmacy combination during the study period
  4. Time (%) represents the percentage of time, of the total study period, during which each combination has been used
  5. For each family, two or more concomitant treatments can be included