Skip to main content

Table 3 Research questions- substance (drug and/ or alcohol) use disorders

From: Gaps and challenges: WHO treatment recommendations for tobacco cessation and management of substance use disorders in people with severe mental illness

For people with SMD and substance (drug and/or alcohol) use disorder, are pharmacological and/or non-pharmacological interventions for substance use disorder effective to support reduction in substance use-related outcomes?
Population/ Intervention / Comparison / Outcome (PICO)
Population: people with SMD and substance (drug and/or alcohol) use disorder
Intervention:
pharmacological and/or non-pharmacological interventions for substance use disorders:
- Pharmacological interventions
- Non-pharmacological interventions: e.g. motivational interviewing and/or CBT, psychoeducation, brief assessment interview, dual-focus interventions
Comparison: care as usual / placebo or one treatment vs another
Outcomes:
Critical
- Level of consumption
- Frequency of use
- Abstinence
- Relapse rates
Important:
- Frequency of adverse events / side-effects