Table 2 Demographic and clinical data of patients with possible iNPH and without iNPH (no iNPH) with combined data (present and preceding study)
Characteristics | No iNPH (n = 51) | Possible iNPH (n = 8) | p value |
|---|---|---|---|
Sex, male | 29 | 6 | 1.0 |
Age (years) | 69.0 ± 6.8 | 74.0 ± 8.5 | 0.092 |
BMI (kg/m2) | 20.5 ± 2.5 (46) | 21.9 ± 2.9 (7) | 0.294 |
Smoking | 13 | 0 | 0.176 |
Age of onset (years) | 27.1 ± 12.9 | 25.0 ± 7.9 | 0.912 |
Duration of illness (months) | 41.6 ± 11.3 | 53.9 ± 21.3 | 0.069 |
CP equivalent | 717.0 ± 493.5 | 655.4 ± 497.0 | 0.842 |
Drug administration | |||
 Anticholinergics | 20 | 2 | 0.698 |
 BPRS | 41.8 ± 13.2 | 43.3 ± 13.4 | 0.765 |
 DIEPSS | 5.9 ± 4.5 | 10.9 ± 4.2 | 0.006 |
iNPHGS | |||
 GS-Gait | 0.96 ± 1.1 | 2.3 ± 1.5 | 0.015 |
 GS-Cogn | 1.8 ± 1.2 | 2.5 ± 1.2 | 0.107 |
 GS-Urin | 0.96 ± 1.1 | 1.8 ± 1.7 | 0.178 |
 TUG | 16.4 ± 9.0 (44) | 24.2 ± 14.9 (6) | 0.376 |
 10-m walking test | 15.2 ± 6.1 (44) | 25.2 ± 14.2 (6) | 0.064 |
 GSS | 3.1 ± 3.2 (47) | 7.7 ± 4.8 (6) | 0.009 |
 MMSE | 18.9 ± 5.5 (48) | 16.1 ± 7.2 (7) | 0.317 |
 NPI | 15.8 ± 11.4 | 16.6 ± 22.3 | 0.451 |
 Evans’ Index | 0.28 ± 0.04 | 0.37 ± 0.07 | < 0.001 |
 DESH | 4 | 5 | 0.001 |
APOE ε4+/ε4− | 11 / 40 | 2 / 6 | 1.0 |